A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.
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DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphismsThe DISC locus in psychiatric illnessDISC1-binding proteins in neural development, signalling and schizophreniaGenetic models of sensorimotor gating: relevance to neuropsychiatric disorders.Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology.Prepulse inhibition and genetic mouse models of schizophrenia.The evolution of drug development in schizophrenia: past issues and future opportunities.Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans.Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illnessDevelopmental disruptions in neural connectivity in the pathophysiology of schizophrenia.Association analysis of the PIP4K2A gene on chromosome 10p12 and schizophrenia in the Irish study of high density schizophrenia families (ISHDSF) and the Irish case-control study of schizophrenia (ICCSS).A Disrupted-in-Schizophrenia 1 Gene Variant is Associated with Clinical Symptomatology in Patients with First-Episode PsychosisRole of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction.Prenatal exposure to maternal infection and executive dysfunction in adult schizophrenia.Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population.Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.Linking neurodevelopmental and synaptic theories of mental illness through DISC1Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1.Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders.Association of variants in DISC1 with psychosis-related traits in a large population cohortMutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference: a comorbidity model.Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypesDISC1 is associated with cortical thickness and neural efficiencyCommon functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents.Cortical mapping of genotype-phenotype relationships in schizophrenia.AKT/GSK3 signaling pathway and schizophreniaAggregated proteins in schizophrenia and other chronic mental diseases: DISC1opathiesDISC1 and Striatal Volume: A Potential Risk Phenotype For mental Illness.Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice.Schizophrenia genetics: uncovering positional candidate genes.Genetic association of cyclic AMP signaling genes with bipolar disorder.Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness.DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia.Opportunities and challenges of psychiatric drug discovery: roles for scientists in academic, industry, and government settings.Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.Approaches for unraveling the joint genetic determinants of schizophrenia and bipolar disorderAssociation between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.
P2860
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P2860
A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
A haplotype within the DISC1 g ...... high density of schizophrenia.
@en
A haplotype within the DISC1 g ...... high density of schizophrenia.
@nl
type
label
A haplotype within the DISC1 g ...... high density of schizophrenia.
@en
A haplotype within the DISC1 g ...... high density of schizophrenia.
@nl
prefLabel
A haplotype within the DISC1 g ...... high density of schizophrenia.
@en
A haplotype within the DISC1 g ...... high density of schizophrenia.
@nl
P2093
P2860
P50
P356
P1433
P1476
A haplotype within the DISC1 g ...... high density of schizophrenia.
@en
P2093
Lönnqvist J
Peltonen L
Tuulio-Henriksson A
P2860
P2888
P304
P356
10.1038/SJ.MP.4001731
P407
P577
2005-12-01T00:00:00Z