Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling.
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GRK2: multiple roles beyond G protein-coupled receptor desensitizationG-protein-coupled receptor kinases in inflammation and diseaseTargeting G protein coupled receptor-related pathways as emerging molecular therapiesGRK2 in the heart: a GPCR kinase and beyondG protein-coupled receptor kinase 2: a link between myocardial contractile function and cardiac metabolism"Freeze, Don't Move": How to Arrest a Suspect in Heart Failure - A Review on Available GRK2 InhibitorsLife Is Simple-Biologic Complexity Is an EpiphenomenonThe expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development.G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.Role of G protein-coupled receptor kinase-2 in peroxisome proliferator-activated receptor gamma-mediated modulation of blood pressure and renal vascular reactivity in SHR.MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult heartsG protein-coupled Receptor Kinase 2 as a Therapeutic Target for Heart Failure.G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progressionReduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarctionRapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation.Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmissionSmall molecule disruption of G beta gamma signaling inhibits the progression of heart failuresi-RNA-Mediated Silencing of ADRBK1 Gene Attenuates Breast Cancer Cell Proliferation.Targeting G protein-coupled receptor kinases (GRKs) in Heart Failure.Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic PathwaySex and age dimorphism of myocardial gene expression in nonischemic human heart failure.Mammalian enabled (Mena) is a critical regulator of cardiac function.Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling.Cell-specific roles of GRK2 in onset and severity of hypoxic-ischemic brain damage in neonatal mice.GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain.Effects of GRK5 and ADRB1 polymorphisms influence on systolic heart failureG protein coupled receptor kinases as therapeutic targets in cardiovascular disease.Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failureRole of myeloid-specific G-protein coupled receptor kinase-2 in sepsis.G protein-coupled receptor kinases: more than just kinases and not only for GPCRsGRK2 and β-arrestins in cardiovascular disease: Something old, something new.Bacillus bombysepticus α-Toxin Binding to G Protein-Coupled Receptor Kinase 2 Regulates cAMP/PKA Signaling Pathway to Induce Host Death.Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophyThe evolving impact of g protein-coupled receptor kinases in cardiac health and diseaseElimination of GRK2 from cholinergic neurons reduces behavioral sensitivity to muscarinic receptor activationHematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice.Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases.Enhanced Uterine Contractility and Stillbirth in Mice Lacking G Protein-Coupled Receptor Kinase 6 (GRK6): Implications for Oxytocin Receptor DesensitizationAstrocyte GRK2 as a novel regulator of glutamate transport and brain damage.GRK2: putting the brakes on the circadian clock.
P2860
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P2860
Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Cardiac-specific ablation of G ...... and beta-adrenergic signaling.
@en
Cardiac-specific ablation of G ...... and beta-adrenergic signaling.
@nl
type
label
Cardiac-specific ablation of G ...... and beta-adrenergic signaling.
@en
Cardiac-specific ablation of G ...... and beta-adrenergic signaling.
@nl
prefLabel
Cardiac-specific ablation of G ...... and beta-adrenergic signaling.
@en
Cardiac-specific ablation of G ...... and beta-adrenergic signaling.
@nl
P2093
P1433
P1476
Cardiac-specific ablation of G ...... and beta-adrenergic signaling.
@en
P2093
Abhinav Diwan
Amy M Odley
Daniel J Hammer
Eric W Brunskill
Gerald W Dorn
Justin L Klanke
Robert J Schwartz
Scot J Matkovich
Walter J Koch
Yehia Marreez
P304
P356
10.1161/01.RES.0000247932.71270.2C
P577
2006-09-28T00:00:00Z