Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.
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Human T cell aging and the impact of persistent viral infectionsImmune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infectionAging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammationIs immunosenescence influenced by our lifetime "dose" of exercise?Cytomegalovirus Infection and Memory T Cell InflationThe aging lungImmunosenescence and organ transplantationImmunologic changes in frail older adultsImmune regulation of human herpesviruses and its implications for human transplantationUnderstanding frailty, aging, and inflammation in HIV infectionMolecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell RepertoirePartners in Crime: The Role of CMV in Immune Dysregulation and Clinical Outcome During HIV InfectionHerpesvirus reactivation and socioeconomic position: a community-based studyAging and immune function: molecular mechanisms to interventionsPTSD is associated with an increase in aged T cell phenotypes in adults living in DetroitNaïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirusNatural CD4+ T-cell responses against indoleamine 2,3-dioxygenaseBioactive Nutrients and Nutrigenomics in Age-Related Diseases.T cell senescence and cardiovascular diseases.High frequency of herpesvirus-specific clonotypes in the human T cell repertoire can remain stable over decades with minimal turnoverCMV pp65 and IE-1 T cell epitopes recognized by healthy subjects.Accurate identification of paraprotein antigen targets by epitope reconstruction.Differences between naive and memory T cell phenotype in Malawian and UK adolescents: a role for Cytomegalovirus?Individual characterization of stably expanded T cell clones in ankylosing spondylitis patients.Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.Cytomegalovirus drives Vδ2neg γδ T cell inflation in many healthy virus carriers with increasing age.Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer's disease.Abnormalities of the alphabeta T-cell receptor repertoire in advanced myelodysplastic syndrome.Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons.Differential Effect of Cytomegalovirus Infection with Age on the Expression of CD57, CD300a, and CD161 on T-Cell Subpopulations.Is HIV a model of accelerated or accentuated aging?Highly functional T-cell receptor repertoires are abundant in stem memory T cells and highly shared among individuals.CD8+ memory T-cell inflation renders compromised CD4+ T-cell-dependent CD8+ T-cell immunity via naïve T-cell anergy.Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis.Use of a murine cytomegalovirus K181-derived bacterial artificial chromosome as a vaccine vector for immunocontraception.Long-term maintenance of diphtheria-specific antibodies after booster vaccination is hampered by latent infection with Cytomegalovirus.IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients.Cytotoxic potential of lung CD8(+) T cells increases with chronic obstructive pulmonary disease severity and with in vitro stimulation by IL-18 or IL-15.Cytomegalovirus infection- and age-dependent changes in human CD8+ T-cell cytokine expression patternsThe blood of healthy individuals exhibits CD8 T cells with a highly altered TCR Vb repertoire but with an unmodified phenotype
P2860
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P2860
Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Cytomegalovirus seropositivity ...... n healthy elderly individuals.
@en
Cytomegalovirus seropositivity ...... n healthy elderly individuals.
@nl
type
label
Cytomegalovirus seropositivity ...... n healthy elderly individuals.
@en
Cytomegalovirus seropositivity ...... n healthy elderly individuals.
@nl
prefLabel
Cytomegalovirus seropositivity ...... n healthy elderly individuals.
@en
Cytomegalovirus seropositivity ...... n healthy elderly individuals.
@nl
P2093
P1476
Cytomegalovirus seropositivity ...... n healthy elderly individuals.
@en
P2093
Alan J Sinclair
Jenni A Ainsworth
Laxman Nayak
Mark Cobbold
Naeem Khan
Naseer Shariff
Paul A H Moss
Rachel Bruton
P304
P356
10.4049/JIMMUNOL.169.4.1984
P407
P577
2002-08-01T00:00:00Z