Key issues in the computational simulation of GPCR function: representation of loop domains.
about
Membrane protein prediction methodsComparative modelling of protein structure and its impact on microbial cell factories.Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors.Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.Structural insights into human GPCR protein OA1: a computational perspective.Modeling flexible loops in the dark-adapted and activated states of rhodopsin, a prototypical G-protein-coupled receptor.Probing a model of a GPCR/ligand complex in an explicit membrane environment: the human cholecystokinin-1 receptor.Probing the structural determinants for the function of intracellular loop 2 in structurally cognate G-protein-coupled receptors.Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: calculation of structural and dynamic properties.Computational methods in drug design: modeling G protein-coupled receptor monomers, dimers, and oligomersMolecular dynamics simulation of the P2Y14 receptor. Ligand docking and identification of a putative binding site of the distal hexose moiety.The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice.Heavier-than-air flying machines are impossible.Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptors.Advances in the Development and Application of Computational Methodologies for Structural Modeling of G-Protein Coupled Receptors.Comparative docking study of anibamine as the first natural product CCR5 antagonist in CCR5 homology models.Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3.Monte Carlo loop refinement and virtual screening of the thyroid-stimulating hormone receptor transmembrane domain.Homology modeling and molecular dynamics simulations of the mu opioid receptor in a membrane-aqueous system.Methods for the Development of In Silico GPCR Models.
P2860
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P2860
Key issues in the computational simulation of GPCR function: representation of loop domains.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
@zh-hant
name
Key issues in the computationa ...... epresentation of loop domains.
@en
Key issues in the computationa ...... epresentation of loop domains.
@nl
type
label
Key issues in the computationa ...... epresentation of loop domains.
@en
Key issues in the computationa ...... epresentation of loop domains.
@nl
prefLabel
Key issues in the computationa ...... epresentation of loop domains.
@en
Key issues in the computationa ...... epresentation of loop domains.
@nl
P356
P1476
Key issues in the computationa ...... representation of loop domains
@en
P2093
E L Mehler
S A Hassan
P2888
P304
P356
10.1023/A:1023845015343
P577
2002-11-01T00:00:00Z
P6179
1011123885