A model for the stoichiometric regulation of blood coagulation.
about
Systems biology of coagulationModels for thrombin generation and risk of diseaseMultiscale systems biology and physics of thrombosis under flow.Microfluidics and coagulation biologyFrom principle to practice: bridging the gap in patient profilingComputationally derived points of fragility of a human cascade are consistent with current therapeutic strategiesEvaluation of the efficacy and safety of rivaroxaban using a computer model for blood coagulationRandom Forests Are Able to Identify Differences in Clotting Dynamics from Kinetic Models of Thrombin GenerationAnticoagulants and the propagation phase of thrombin generationCofactor activity in factor VIIIa of the blood clotting pathway is stabilized by an interdomain bond between His281 and Ser524 formed in factor VIII.A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation.Multiscale prediction of patient-specific platelet function under flowMultiscale simulation of thrombus growth and vessel occlusion triggered by collagen/tissue factor using a data-driven model of combinatorial platelet signalling.The effect of high circulating estradiol levels on thrombin generation during in vitro fertilization.Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood.A multiscale model of venous thrombus formation with surface-mediated control of blood coagulation cascade.Taking the thrombin "fork".Kinetic model facilitates analysis of fibrin generation and its modulation by clotting factors: implications for hemostasis-enhancing therapies.Factor Xa generation by computational modeling: an additional discriminator to thrombin generation evaluation.Defining the boundaries of normal thrombin generation: investigations into hemostasisPlasma factor and inhibitor composition contributes to thrombin generation dynamics in patients with acute or previous cerebrovascular eventsModeling of human factor Va inactivation by activated protein C.The tissue factor requirement in blood coagulation.Thrombin generation profiles in deep venous thrombosis.Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor.The plasma hemostatic proteome: thrombin generation in healthy individuals.Dilutional control of prothrombin activation at physiologically relevant shear ratesCellular regulation of blood coagulation: a model for venous stasisBlood coagulation dynamics in haemostasis.What is all that thrombin for?Soluble phosphatidylserine binds to two sites on human factor IXa in a Ca2+ dependent fashion to specifically regulate structure and activityIntroduction to haemostasis from a pharmacodynamic perspectiveCanalization effect in the coagulation cascade and the interindividual variability of oral anticoagulant response. A simulation studyClotting factor deficiency in early trauma-associated coagulopathy.Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited.Regulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach.Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow.Does the genotype predict the phenotype? Evaluations of the hemostatic proteome.Sequences flanking Arg336 in factor VIIIa modulate factor Xa-catalyzed cleavage rates at this site and cofactor function.Is there value in kinetic modeling of thrombin generation? Yes.
P2860
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P2860
A model for the stoichiometric regulation of blood coagulation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
A model for the stoichiometric regulation of blood coagulation.
@en
A model for the stoichiometric regulation of blood coagulation.
@nl
type
label
A model for the stoichiometric regulation of blood coagulation.
@en
A model for the stoichiometric regulation of blood coagulation.
@nl
prefLabel
A model for the stoichiometric regulation of blood coagulation.
@en
A model for the stoichiometric regulation of blood coagulation.
@nl
P2093
P2860
P356
P1476
A model for the stoichiometric regulation of blood coagulation.
@en
P2093
Kenneth C Jones
Kenneth G Mann
Matthew F Hockin
Stephen J Everse
P2860
P304
18322-18333
P356
10.1074/JBC.M201173200
P407
P577
2002-03-13T00:00:00Z