Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow.
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Systems biology of coagulationMultiscale systems biology and physics of thrombosis under flow.Microfluidics and coagulation biologyThe effect of factor VIII deficiencies and replacement and bypass therapies on thrombus formation under venous flow conditions in microfluidic and computational modelsIn microfluidico: Recreating in vivo hemodynamics using miniaturized devicesBlood flow controls coagulation onset via the positive feedback of factor VII activation by factor Xa.Multiscale prediction of patient-specific platelet function under flowPlatelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse.Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood.Thrombin flux and wall shear rate regulate fibrin fiber deposition state during polymerization under flow.Task-oriented modular decomposition of biological networks: trigger mechanism in blood coagulation.Improvement of spatial fibrin formation by the anti-TFPI aptamer BAX499: changing clot size by targeting extrinsic pathway initiation.Shaping the platelet response to vascular injury.A combined microfluidic-microstencil method for patterning biomolecules and cellsSimulated surface-induced thrombin generation in a flow fieldPositive feedback loops for factor V and factor VII activation supply sensitivity to local surface tissue factor density during blood coagulation.Relipidated tissue factor linked to collagen surfaces potentiates platelet adhesion and fibrin formation in a microfluidic model of vessel injury.P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions.Blood clot formation under flow: the importance of factor XI depends strongly on platelet count.Membrane binding events in the initiation and propagation phases of tissue factor-initiated zymogen activation under flow.Thrombus growth and embolism on tissue factor-bearing collagen surfaces under flow: role of thrombin with and without fibrin.Modeling and simulation of procoagulant circulating tumor cells in flow.Grow with the flow: a spatial-temporal model of platelet deposition and blood coagulation under flowSimulated Thrombin Generation in the Presence of Surface-Bound Heparin and Circulating Tissue FactorThe role of carrier number on the procoagulant activity of tissue factor in blood and plasma.Matrix metalloproteases and PAR1 activation.Rivaroxaban delivery and reversal at a venous flow rateSystems Analysis of Thrombus Formation.Simulated thrombin responses in venous valves.Tissue factor in coagulation: Which? Where? When?Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stabilityMicrofluidic assay of hemophilic blood clotting: distinct deficits in platelet and fibrin deposition at low factor levels.Tissue factor activity under flow.Analysis of tissue factor positive microparticles.Serine and metalloprotease signaling through PAR1 in arterial thrombosis and vascular injury.Monitoring in vitro thrombus formation with novel microfluidic devices.The effects of arterial flow on platelet activation, thrombus growth, and stabilization.Fluid Mechanics of Blood Clot Formation.Transport physics and biorheology in the setting of hemostasis and thrombosis.A microfluidic model of hemostasis sensitive to platelet function and coagulation.
P2860
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P2860
Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Determination of surface tissu ...... g tissue factor requires flow.
@ast
Determination of surface tissu ...... g tissue factor requires flow.
@en
type
label
Determination of surface tissu ...... g tissue factor requires flow.
@ast
Determination of surface tissu ...... g tissue factor requires flow.
@en
prefLabel
Determination of surface tissu ...... g tissue factor requires flow.
@ast
Determination of surface tissu ...... g tissue factor requires flow.
@en
P2093
P2860
P1433
P1476
Determination of surface tissu ...... ng tissue factor requires flow
@en
P2093
Keith B Neeves
Manash S Chatterjee
Scott L Diamond
Uzoma M Okorie
P2860
P304
P356
10.1182/BLOOD-2007-08-106229
P407
P577
2008-01-18T00:00:00Z