Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
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Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genesHepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissuesLoss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in miceExpression and localization of P1 promoter-driven hepatocyte nuclear factor-4alpha (HNF4alpha) isoforms in human and ratsCREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expressionIn vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryoThe tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryoFunctions of HNF1 family members in differentiation of the visceral endoderm cell lineageAn alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell typesHepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasisThe endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages.Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinomaGene expression profiles in developing nephrons using Lim1 metanephric mesenchyme-specific conditional mutant mice.Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in miceHepatocyte nuclear factor-4alpha induces transdifferentiation of hematopoietic cells into hepatocytesIdentification of cis-regulatory sequences in the human angiotensinogen gene by transgene coplacement and site-specific recombination.The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.A transcription factor regulatory circuit in differentiated pancreatic cells.ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems.Inhibitor of the tissue-specific transcription factor HNF4, a potential regulator in early Xenopus development.Induction of highly functional hepatocytes from human umbilical cord mesenchymal stem cells by HNF4α transductionTransitions between epithelial and mesenchymal states and the morphogenesis of the early mouse embryo.Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells.The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult mouse kidney.HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells.Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.Transcriptional Factors Mediating Retinoic Acid Signals in the Control of Energy MetabolismHepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells.HNF4beta, a new gene of the HNF4 family with distinct activation and expression profiles in oogenesis and embryogenesis of Xenopus laevisHepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colonEarly Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.Identification of HNF-4α as a key transcription factor to promote ChREBP expression in response to glucoseEffects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of the young.Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein HThe activation function-1 of hepatocyte nuclear factor-4 is an acidic activator that mediates interactions through bulky hydrophobic residues.Generation of inhibitory mutants of hepatocyte nuclear factor 4.An enhancer element 6 kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors.Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium.Regulatory mechanisms controlling human hepatocyte nuclear factor 4alpha gene expression.
P2860
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P2860
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
@en
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
@nl
type
label
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
@en
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
@nl
prefLabel
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
@en
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
@nl
P1476
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
@en
P2093
P356
10.1016/0925-4773(94)90017-5
P577
1994-11-01T00:00:00Z