The retinal degeneration slow (rds) gene product is a photoreceptor disc membrane-associated glycoprotein.
about
Biology and therapy of inherited retinal degenerative disease: insights from mouse modelsPhotoreceptor renewal: a role for peripherin/rdsMutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophyFolding and subunit assembly of photoreceptor peripherin/rds is mediated by determinants within the extracellular/intradiskal EC2 domain: implications for heterogeneous molecular pathologies.The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesisA monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in miceThe intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenanceGenetic variations strongly influence phenotypic outcome in the mouse retina.Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors.The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells.Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa.Disulfide-mediated oligomerization of Peripherin/Rds and Rom-1 in photoreceptor disk membranes. Implications for photoreceptor outer segment morphogenesis and degeneration.Uncoupling of photoreceptor peripherin/rds fusogenic activity from biosynthesis, subunit assembly, and targeting: a potential mechanism for pathogenic effects.Molecular diagnosis of putative Stargardt Disease probands by exome sequencingGene therapy for PRPH2-associated ocular disease: challenges and prospectsPredicted and measured disorder in peripherin/rds, a retinal tetraspanin.Rod photoreceptor temporal properties in retinitis pigmentosa.The function of oligomerization-incompetent RDS in rodsLate-onset autosomal dominant macular dystrophy with choroidal neovascularization and nonexudative maculopathy associated with mutation in the RDS gene.The genetics of inherited macular dystrophies.Light regulates the ciliary protein transport and outer segment disc renewal of mammalian photoreceptors.Investigation of disease mechanisms in retinitis pigmentosa.Founder Effect of a c.828+3A>T Splice Site Mutation in Peripherin 2 (PRPH2) Causing Autosomal Dominant Retinal Dystrophies.The role of subunit assembly in peripherin-2 targeting to rod photoreceptor disk membranes and retinitis pigmentosa.Genetic factors of age-related macular degeneration.Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated murine opsin gene.Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosaLocalization of peripherin/rds in the disk membranes of cone and rod photoreceptors: relationship to disk membrane morphogenesis and retinal degenerationDifferential localizations of and requirements for the two Drosophila ninaC kinase/myosins in photoreceptor cells.Autosomal Dominant Retinal Dystrophies Caused by a Founder Splice Site Mutation, c.828+3A>T, in PRPH2 and Protein Haplotypes in trans as Modifiers.Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene.Deletional analysis of the rod photoreceptor cell peripherin/RDS carboxy-terminal regionStable and efficient gene transfer into the retina using an HIV-based lentiviral vector.The role of Rds in outer segment morphogenesis and human retinal disease.A tetraspan membrane glycoprotein produced in the human intestinal epithelium and liver that can regulate cell density-dependent proliferation.PRPH2/RDS and ROM-1: Historical context, current views and future considerations.Identification of candidate genes for human retinal degeneration loci using differentially expressed genes from mouse photoreceptor dystrophy modelsA novel mutation in Prph2, a gene regulated by Nr2e3, causes retinal degeneration and outer-segment defects similar to Nr2e3 ( rd7/rd7 ) retinas.The C terminus of peripherin/rds participates in rod outer segment targeting and alignment of disk incisures.Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations
P2860
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P2860
The retinal degeneration slow (rds) gene product is a photoreceptor disc membrane-associated glycoprotein.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
The retinal degeneration slow ...... brane-associated glycoprotein.
@en
The retinal degeneration slow
@nl
type
label
The retinal degeneration slow ...... brane-associated glycoprotein.
@en
The retinal degeneration slow
@nl
prefLabel
The retinal degeneration slow ...... brane-associated glycoprotein.
@en
The retinal degeneration slow
@nl
P2093
P1433
P1476
The retinal degeneration slow ...... brane-associated glycoprotein.
@en
P2093
P356
10.1016/0896-6273(91)90122-G
P407
P577
1991-01-01T00:00:00Z