Steady-state kinetic mechanism of rat tyrosine hydroxylase.
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Mechanism of aromatic amino acid hydroxylationInsights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylationMechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic AnalysisIdentification of iron ligands in tyrosine hydroxylase by mutagenesis of conserved histidinyl residuesCharacterization of the active site iron in tyrosine hydroxylase. Redox states of the ironSpectroscopy and kinetics of wild-type and mutant tyrosine hydroxylase: mechanistic insight into O2 activationMeasurement of intrinsic rate constants in the tyrosine hydroxylase reactionTyrosine HydroxylaseA unique dual activity amino acid hydroxylase in Toxoplasma gondii.Direct spectroscopic evidence for a high-spin Fe(IV) intermediate in tyrosine hydroxylase.Mechanisms of tryptophan and tyrosine hydroxylase.The rate-limiting step of O2 activation in the α-ketoglutarate oxygenase factor inhibiting hypoxia inducible factor.Effects of phosphorylation by protein kinase A on binding of catecholamines to the human tyrosine hydroxylase isoforms.Effects of mutations in tyrosine hydroxylase associated with progressive dystonia on the activity and stability of the protein.Allosteric regulation of phenylalanine hydroxylase.Complex molecular regulation of tyrosine hydroxylase.A heme peroxidase with a functional role as an L-tyrosine hydroxylase in the biosynthesis of anthramycin.Structure and function of the aromatic amino acid hydroxylases.Catecholamines, hypoxia and high altitude.Fluorescence spectroscopy as a probe of the effect of phosphorylation at serine 40 of tyrosine hydroxylase on the conformation of its regulatory domain.Kinetic mechanism of phenylalanine hydroxylase: intrinsic binding and rate constants from single-turnover experiments.Effects of ligands on the mobility of an active-site loop in tyrosine hydroxylase as monitored by fluorescence anisotropy.Uncoupled forms of tyrosine hydroxylase unmask kinetic isotope effects on chemical steps.Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylaseA flexible loop in tyrosine hydroxylase controls coupling of amino acid hydroxylation to tetrahydropterin oxidation.Expression and purification of recombinant human tyrosine hydroxylase as a fusion protein in Escherichia coli.Purification and characterization of the blue-green rat phaeochromocytoma (PC12) tyrosine hydroxylase with a dopamine-Fe(III) complex. Reversal of the endogenous feedback inhibition by phosphorylation of serine-40.Expression and characterization of catalytic and regulatory domains of rat tyrosine hydroxylaseReal-time monitoring of tyrosine hydroxylase activity using a plate reader assay.Endogenous tetrahydroisoquinolines associated with Parkinson's disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines.
P2860
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P2860
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
@en
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
@nl
type
label
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
@en
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
@nl
prefLabel
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
@en
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
@nl
P356
P1433
P1476
Steady-state kinetic mechanism of rat tyrosine hydroxylase.
@en
P2093
Fitzpatrick PF
P304
P356
10.1021/BI00229A010
P407
P577
1991-04-01T00:00:00Z