Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function.
about
Modulation of cardiac contractility by the phospholamban/SERCA2a regulatomeChamber Specific Gene Expression Landscape of the Zebrafish HeartPlasticity and adaptation of Ca2+ signaling and Ca2+-dependent exocytosis in SERCA2(+/-) mice.Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarizationFunctional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study.Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy.TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction.SERCA2 regulates non-CF and CF airway epithelial cell response to ozoneHistidine-rich calcium binding protein: the new regulator of sarcoplasmic reticulum calcium cycling.Phospholamban interactome in cardiac contractility and survival: A new vision of an old friend.Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency.Shifts in the myosin heavy chain isozymes in the mouse heart result in increased energy efficiency.Heterozygous disruption of SERCA2a is not associated with impairment of cardiac performance in humans: implications for SERCA2a as a therapeutic target in heart failureThe angiotensin receptor-associated protein Atrap is a stimulator of the cardiac Ca2+-ATPase SERCA2a.Mathematical modeling mechanisms of arrhythmias in transgenic mouse heart overexpressing TNF-αDeterminants of frequency-dependent contraction and relaxation of mammalian myocardium.Molecular basis of diastolic dysfunction.Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodelingCalcium pumps in health and disease.Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) gene silencing and remodeling of the Ca2+ signaling mechanism in cardiac myocytes.The Ca2+ pumps of the endoplasmic reticulum and Golgi apparatus.SERCA2a: a prime target for modulation of cardiac contractility during heart failure.The Golgi Apparatus: Panel Point of Cytosolic Ca(2+) Regulation.PM2.5 exposure in utero contributes to neonatal cardiac dysfunction in mice.Trichloroethylene disrupts cardiac gene expression and calcium homeostasis in rat myocytesReduced SERCA2a converts sub-lethal myocardial injury to infarction and affects postischemic functional recovery.In Utero Particulate Matter Exposure Produces Heart Failure, Electrical Remodeling, and Epigenetic Changes at Adulthood.Alteration of expression of Ca2+ signaling proteins and adaptation of Ca2+ signaling in SERCA2+/- mouse parotid acini.Modeling Ca2+ dynamics of mouse cardiac cells points to a critical role of SERCA's affinity for Ca2+.Targeted inhibition of Ca2+/calmodulin-dependent protein kinase II in cardiac longitudinal sarcoplasmic reticulum results in decreased phospholamban phosphorylation at threonine 17.Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes.Altered dose response to beta-agonists in SERCA1a-expressing hearts ex vivo and in vivo.Electrophysiological consequences of human IKs channel expression in adult murine heart.PYK2 regulates SERCA2 gene expression in neonatal rat ventricular myocytes.Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice.Increased susceptibility to ventricular arrhythmias is associated with changes in Ca2+ regulatory proteins in paraplegic rats.Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling.
P2860
Q24337593-80CAB7AD-1E47-4005-9BFF-E0EA875E1DB6Q27324640-C717EFD6-5ED5-49D8-B98C-C1BB1844E783Q28366127-2066F5E8-5222-4C4D-9A56-44BA8E3EBD78Q28654771-8FB58E3C-6D5E-4A37-8570-3F459BEF9A38Q30366617-FACFA742-73B7-4987-B376-1A6C945FAAC4Q33782743-1F51CB83-5028-497B-8F7D-C2E9716998C0Q33810072-3DC70803-2747-47F6-8D96-EACD2134A079Q34077907-9A82D8E3-129A-4DEB-92C6-B287B4210923Q34478686-4D3F76C4-939A-471B-B8B0-A197DC16B914Q35032742-09A9FED2-E246-4378-ACCB-CF361AAA68E8Q35041411-CB635EF1-756A-4507-AB56-22607CFE78FBQ35547989-63C90695-7DA0-4A44-AB3F-5016A6A9318BQ35771932-78CFCD71-B70E-47D4-A022-A50DFFCF594DQ35970623-80995337-CCB5-40B7-9666-FBDE584851E7Q35989007-AC96A4A8-695C-4056-9C34-BAEEAF25FD40Q36962499-001DD226-5EF3-436E-BFDC-0A80EAC794A7Q37099714-F076D262-9588-4267-A70A-F78692C2AB6EQ37529284-414AE315-EC0D-4A51-B170-5E0BB366A847Q37605483-F510D02A-0ABE-4369-B6EB-80C261D4539DQ37621106-E74CE27F-1A32-4A88-B279-C5DB8CC08E09Q37858339-6C62103B-603C-43C4-9B65-EABA464100DFQ38109648-4E2966DF-051B-4ACB-9300-205C0CE33AB8Q38116698-7435ABA3-5BCE-4B79-A0CA-219077AD5D6BQ38709683-5217F355-C9C0-45B7-8CF5-426BE5F8992EQ39001482-B0F6C966-F90E-4AEF-9505-1AE105FB2D24Q40149014-68C1F1AF-09B1-48B0-8B0B-D81B5139688DQ41166374-87EC78E7-3226-4012-AEC5-B80E79CEADB4Q41846752-CC7E63F1-50EF-4F72-A450-BB3BEED4C2C7Q42141286-3DCDA59F-D0DD-4C90-9E01-B81E7E11183EQ42439646-22405D55-ABDA-4911-B5F1-600A9F1FE366Q43216744-FD39CD89-2F00-4C63-BAB4-AE28CC415128Q44103918-B114A64B-00E2-4C66-8C81-6D5402472C09Q44185563-C70F02EF-F872-41C6-BE44-96229484E64CQ46437055-8BB8AC13-0329-45D2-A9DC-CD0190493AC6Q46807746-62AB02FC-9EC6-4929-9E0A-A543FE678BD0Q47327592-374FB962-D24F-41B6-996E-4833B62DD8D0Q47735806-4B76C03B-57BF-4802-BFE5-EA88AC6DD707Q50317783-29494E89-1FD3-4143-A1CD-83E93B2211C0
P2860
Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Disruption of a single copy of ...... is and cardiomyocyte function.
@en
Disruption of a single copy of ...... is and cardiomyocyte function.
@nl
type
label
Disruption of a single copy of ...... is and cardiomyocyte function.
@en
Disruption of a single copy of ...... is and cardiomyocyte function.
@nl
prefLabel
Disruption of a single copy of ...... is and cardiomyocyte function.
@en
Disruption of a single copy of ...... is and cardiomyocyte function.
@nl
P2093
P2860
P356
P1476
Disruption of a single copy of ...... is and cardiomyocyte function.
@en
P2093
D L Kirkpatrick
N Chiamvimonvat
P2860
P304
38073-38080
P356
10.1074/JBC.M004804200
P407
P577
2000-12-01T00:00:00Z