Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
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Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-BTransgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performanceRegulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrinAltered contractility and [Ca2+]i homeostasis in phospholemman-deficient murine myocytes: role of Na+/Ca2+ exchangeOverexpression of the Na(+)/Ca(2+) exchanger and inhibition of the sarcoplasmic reticulum Ca(2+)-ATPase in ventricular myocytes from transgenic mice.A mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform.Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stressesOverexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress.Energetics of Na(+)-Ca(2+) exchange in resting cardiac muscle.Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger.Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchangerEffects of Na+-Ca2+ exchange expression on excitation-contraction coupling in genetically modified mice.Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.Regionally diverse mitochondrial calcium signaling regulates spontaneous pacing in developing cardiomyocytes.Induced overexpression of Na(+)/Ca(2+) exchanger does not aggravate myocardial dysfunction induced by transverse aortic constriction.Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases.Herpesvirus-mediated delivery of a genetically encoded fluorescent Ca(2+) sensor to canine cardiomyocytes.Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration.Designing heart performance by gene transfer.Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1.Cardiac electrophysiology in mice: a matter of size.No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium.Na/Ca exchange and contraction of the heart.Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice.Sodium-calcium exchange inhibitors: therapeutic potential in cardiovascular diseases.Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanismsThe Effects of SEA0400 on Ca2+ Transient Amplitude and Proarrhythmia Depend on the Na+/Ca2+ Exchanger Expression Level in Murine Models.Cardiac hypertrophy in mice expressing unphosphorylatable phospholemman.Activation of reverse Na+-Ca2+ exchange by the Na+ current augments the cardiac Ca2+ transient: evidence from NCX knockout mice.Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes.Recombinant expression of the plasma membrane Na(+)/Ca(2+) exchanger affects local and global Ca(2+) homeostasis in Chinese hamster ovary cells.Overexpression of Na+/Ca2+ exchanger gene attenuates postinfarction myocardial dysfunction.Mice overexpressing the cardiac sodium-calcium exchanger: defects in excitation-contraction coupling.T-type Ca2+ current as a trigger for Ca2+ release from the sarcoplasmic reticulum in guinea-pig ventricular myocytes.Functional role of ionic regulation of Na+/Ca2+ exchange assessed in transgenic mouse hearts.Triggered activity in atrial myocytes is influenced by Na+/Ca2+ exchanger activity in genetically altered mice.Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function.The control of Ca release from the cardiac sarcoplasmic reticulum: regulation versus autoregulation.
P2860
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P2860
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
@ast
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
@en
type
label
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
@ast
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
@en
prefLabel
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
@ast
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
@en
P2093
P2860
P356
P1476
Calcium signaling in transgenic mice overexpressing cardiac Na(+)-Ca2+ exchanger.
@en
P2093
P2860
P304
P356
10.1085/JGP.109.6.717
P577
1997-06-01T00:00:00Z