Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.
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Silencing or knocking out the Na(+)/Ca(2+) exchanger-3 (NCX3) impairs oligodendrocyte differentiation.A Comparative Study of Variables Influencing Ischemic Injury in the Longa and Koizumi Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in MiceIonic regulation of cell volume changes and cell death after ischemic stroke.Ionic storm in hypoxic/ischemic stress: can opioid receptors subside it?The TRPC channel blocker SKF 96365 inhibits glioblastoma cell growth by enhancing reverse mode of the Na(+) /Ca(2+) exchanger and increasing intracellular Ca(2+).Involvement of the sodium-calcium exchanger 3 (NCX3) in ziram-induced calcium dysregulation and toxicity.MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits.Ionic transporter activity in astrocytes, microglia, and oligodendrocytes during brain ischemiaDoes Na⁺/Ca²⁺ exchanger, NCX, represent a new druggable target in stroke intervention?Recent structural and functional insights into the family of sodium calcium exchangers.The role of Na+/Ca2+ exchanger subtypes in neuronal ischemic injury.Novel Cellular Mechanisms for Neuroprotection in Ischemic Preconditioning: A View from Inside Organelles.Endoplasmic reticulum stress in brain ischemia.Glial Na(+) -dependent ion transporters in pathophysiological conditions.A new cell-penetrating peptide that blocks the autoinhibitory XIP domain of NCX1 and enhances antiporter activity.Plasma membrane Ca2+-ATPase overexpression depletes both mitochondrial and endoplasmic reticulum Ca2+ stores and triggers apoptosis in insulin-secreting BRIN-BD11 cells.Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via AktInvolvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation.The NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning.ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na+ /Ca2+ exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells.ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioningHigh levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease.Ncx3 gene ablation impairs oligodendrocyte precursor response and increases susceptibility to experimental autoimmune encephalomyelitis.Reverse NCX Attenuates Cellular Sodium Loading in Metabolically Compromised Cortex.Synergistic Association of Valproate and Resveratrol Reduces Brain Injury in Ischemic Stroke.Glycine release provoked by disturbed Na⁺, Na⁺ and Ca²⁺ homeostasis in cerebellar nerve endings: roles of Ca²⁺ channels, Na⁺/Ca²⁺ exchangers and GlyT2 transporter reversal.NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson's Disease.
P2860
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P2860
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Targeted disruption of Na+/Ca2 ...... ning of ischemic brain damage.
@en
Targeted disruption of Na+/Ca2+ exchanger 3
@nl
type
label
Targeted disruption of Na+/Ca2 ...... ning of ischemic brain damage.
@en
Targeted disruption of Na+/Ca2+ exchanger 3
@nl
prefLabel
Targeted disruption of Na+/Ca2 ...... ning of ischemic brain damage.
@en
Targeted disruption of Na+/Ca2+ exchanger 3
@nl
P2093
P50
P1476
Targeted disruption of Na+/Ca2 ...... ning of ischemic brain damage.
@en
P2093
Andre Herchuelz
Antonella Scorziello
Gianfranco Di Renzo
Rosaria Gala
Rossana Sirabella
Sophie Sokolow
Stèphane Schurmans
P304
P356
10.1523/JNEUROSCI.4671-07.2008
P407
P50
P577
2008-01-01T00:00:00Z