Functional role of the "ionic lock"--an interhelical hydrogen-bond network in family A heptahelical receptors.
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Kiwi genome provides insights into evolution of a nocturnal lifestyleStructure and function of an irreversible agonist-β(2) adrenoceptor complexIdentification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observationsThe 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonistHydrogen bond dynamics in membrane protein functionA constitutively active G protein-coupled acetylcholine receptor regulates motility of larval Schistosoma mansoniStructure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective AntagonistThe structural basis of agonist-induced activation in constitutively active rhodopsinStructure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and CaffeineStructure of the agonist-bound neurotensin receptorStabilized G protein binding site in the structure of constitutively active metarhodopsin-IINew mechanism for voltage induced charge movement revealed in GPCRs--theory and experimentsHomology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluationHow genetic errors in GPCRs affect their function: Possible therapeutic strategiesThe structure and function of G-protein-coupled receptorsMolecular simulations and solid-state NMR investigate dynamical structure in rhodopsin activation.Structure-function of the G protein-coupled receptor superfamily.Structure-based simulations reveal concerted dynamics of GPCR activationThe essential role for aromatic cluster in the β3 adrenergic receptorRearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptorsSequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate.Structure and function of G protein-coupled receptors using NMR spectroscopy.Ligand-induced modulation of the free-energy landscape of G protein-coupled receptors explored by adaptive biasing techniquesA yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunitsAdaptation of pineal expressed teleost exo-rod opsin to non-image forming photoreception through enhanced Meta II decay.Structural insights into human GPCR protein OA1: a computational perspective.Transient protonation changes in channelrhodopsin-2 and their relevance to channel gatingHighly conserved tyrosine stabilizes the active state of rhodopsin.Coupling of retinal, protein, and water dynamics in squid rhodopsin.Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.Energy landscapes as a tool to integrate GPCR structure, dynamics, and function.Discovery of new GPCR biology: one receptor structure at a time.The significance of G protein-coupled receptor crystallography for drug discovery.Activation mechanism of the β2-adrenergic receptor.Differential determinants for coupling of distinct G proteins with the class B secretin receptor.Differential Virtual Screening (DVS) with Active and Inactive Molecular Models for Finding and Profiling GPCR Modulators: Case of the CCK1 Receptor.Structural and Functional Effect of an Oscillating Electric Field on the Dopamine-D3 Receptor: A Molecular Dynamics Simulation Study.Structural differences and differential expression among rhabdomeric opsins reveal functional change after gene duplication in the bay scallop, Argopecten irradians (Pectinidae).The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation.Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor
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P2860
Functional role of the "ionic lock"--an interhelical hydrogen-bond network in family A heptahelical receptors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Functional role of the "ionic ...... mily A heptahelical receptors.
@en
Functional role of the "ionic ...... mily A heptahelical receptors.
@nl
type
label
Functional role of the "ionic ...... mily A heptahelical receptors.
@en
Functional role of the "ionic ...... mily A heptahelical receptors.
@nl
prefLabel
Functional role of the "ionic ...... mily A heptahelical receptors.
@en
Functional role of the "ionic ...... mily A heptahelical receptors.
@nl
P2093
P50
P1476
Functional role of the "ionic ...... amily A heptahelical receptors
@en
P2093
Friedrich Siebert
Mohana Mahalingam
Reiner Vogel
P304
P356
10.1016/J.JMB.2008.05.022
P407
P577
2008-05-17T00:00:00Z