Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions.

Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions.

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http://www.wikidata.org/entity/Q52603674
The genome of the kinetoplastid parasite, Leishmania majorIdentification of genes encoding arabinosyltransferases (SCA) mediating developmental modifications of lipophosphoglycan required for sand fly transmission of leishmania major.Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern.Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species.Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactions.Intraspecies variation in Trypanosoma cruzi GPI-mucins: biological activities and differential expression of α-galactosyl residues.Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1.Probing elongating and branching β-D-galactosyltransferase activities in Leishmania parasites by making use of synthetic phosphoglycansComparative genomics: from genotype to disease phenotype in the leishmaniases.The LPG1 gene family of Leishmania major.Reduced antimony accumulation in ARM58-overexpressing Leishmania infantum.Transcriptional inhibition of interleukin-12 promoter activity in Leishmania spp.-infected macrophages.Two functionally divergent UDP-Gal nucleotide sugar transporters participate in phosphoglycan synthesis in Leishmania major.UDP-glycosyltransferase genes in trypanosomatid genomes have diversified independently to meet the distinct developmental needs of parasite adaptations.Lower galactosylation levels of the Lipophosphoglycan from Leishmania (Leishmania) major-like strains affect interaction with Phlebotomus papatasi and Lutzomyia longipalpis.Leptomonas pyrrhocoris: Genomic insight into Parasite's Physiology.Reverse Epidemiology: An Experimental Framework to Drive Biomarker Discovery by Functional Genetic Screening Using Relevant Animal Models
P2860

Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions.

Item
http://www.wikidata.org/entity/Q52603674
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-cn
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2003年學術文章
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name
Functional identification of g ...... a major-sand fly interactions.
@en
Functional identification of galactosyltransferases
@nl
type
label
Functional identification of g ...... a major-sand fly interactions.
@en
Functional identification of galactosyltransferases
@nl
prefLabel
Functional identification of g ...... a major-sand fly interactions.
@en
Functional identification of galactosyltransferases
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Functional identification of g ...... a major-sand fly interactions.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921