Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

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Clinical Features of 167 Inpatients with Autosomal Dominant Polycystic Kidney Disease at a Single Center in China

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Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

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Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

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Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

@en

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

@nl

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Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

@en

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

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P1476

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

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Ebony M Flowers

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Glenda Mernaugh

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Jessica Sudderth

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Lauren Zacharias

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Ralph J DeBerardinis

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Roy Zent

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Thomas J Carroll

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P2860

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells

The LKB1 tumor suppressor negatively regulates mTOR signaling

Cancer cell metabolism: Warburg and beyond

The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4

Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system

LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

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s41467-018-03036-y

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scholarly article

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10.1038/S41467-018-03036-Y

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English

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2018-02-26T00:00:00Z

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29483507

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5827653

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Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

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P2860

P2860

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

description

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type

label

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P698

P932