ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial-mesenchymal transition and enhancing DNA damage.

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ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial-mesenchymal transition and enhancing DNA damage.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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ZEB1 inhibition sensitizes cel ...... tion and enhancing DNA damage.

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ZEB1 inhibition sensitizes cel ...... tion and enhancing DNA damage.

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ZEB1 inhibition sensitizes cel ...... tion and enhancing DNA damage.

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ZEB1 inhibition sensitizes cel ...... tion and enhancing DNA damage.

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ZEB1 inhibition sensitizes cel ...... tion and enhancing DNA damage.

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ZEB1 inhibition sensitizes cel ...... tion and enhancing DNA damage.

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P1476

ZEB1 inhibition sensitizes cel ...... tion and enhancing DNA damage.

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Ce Li

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Heming Li

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Kai Wang

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Kezuo Hou

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Ming Bai

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Na Song

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Wei Jing

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Xiaofang Che

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Xiujuan Qu

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Yanrong Li

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ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance

EMT, CTCs and CSCs in tumor relapse and drug-resistance

Cell cycle checkpoint signaling through the ATM and ATR kinases

Cetuximab-induced MET activation acts as a novel resistance mechanism in colon cancer cells.

Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.

ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.

The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

Gas6/Axl Axis Contributes to Chemoresistance and Metastasis in Breast Cancer through Akt/GSK-3β/β-catenin Signaling.

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595-604

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scholarly article

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10.1080/15384101.2017.1404206

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2017-11-20T00:00:00Z

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29157079

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5969561

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