Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
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The role of NKT cells in tumor immunityThe BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functionsHomotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentCritical roles of RasGRP1 for invariant NKT cell developmentIL-15 regulates homeostasis and terminal maturation of NKT cellsThe transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage.The Ras/MAPK pathway is required for generation of iNKT cells.Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogenyDisposal of iNKT cell deficiency and an increase in expression of SLAM signaling factors characterizes sarcoidosis remission: a 4-year longitudinal study.Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell.Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cellsDifferential requirements for the Ets transcription factor Elf-1 in the development of NKT cells and NK cellsInnate self recognition by an invariant, rearranged T-cell receptor and its immune consequences.Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development.The split personality of NKT cells in malignancy, autoimmune and allergic disordersA unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice.Signaling for NKT cell development: the SAP-FynT connectionA natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage.CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cellsSAP is required for the development of innate phenotype in H2-M3--restricted Cd8(+) T cells.Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product.Characterization of the early stages of thymic NKT cell development.Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes.SAP expression in T cells, not in B cells, is required for humoral immunity.Selection of self-reactive T cells in the thymus.Requirements for selection of conventional and innate T lymphocyte lineages.The transcriptional repressor NKAP is required for the development of iNKT cellsCritical role for miR-181a/b-1 in agonist selection of invariant natural killer T cellsDiacylglycerol kinases: regulated controllers of T cell activation, function, and development.Regulation of thymic NKT cell development by the B7-CD28 costimulatory pathwayRole of diacylglycerol kinases in T cell development and function.The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cellsActivation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling.SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions.Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.Control of early stages in invariant natural killer T-cell development.Orchestration of invariant natural killer T cell development by E and Id proteins.Differential requirement for the SAP-Fyn interaction during NK T cell development and function.Translational control of NKT cell cytokine production by p38 MAPK.
P2860
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P2860
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
@en
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
@nl
type
label
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
@en
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
@nl
prefLabel
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
@en
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.
@nl
P1476
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice
@en
P2093
Lowin-Kropf B
MacDonald HR
P304
P407
P50
P577
1999-10-01T00:00:00Z