Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
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Diagnosis and subclassification of acute lymphoblastic leukemiaThe relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemiaIL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing StudyLoss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemiaTargeting the MYC and PI3K pathways eliminates leukemia-initiating cells in T-cell acute lymphoblastic leukemiaTenovin-6-mediated inhibition of SIRT1/2 induces apoptosis in acute lymphoblastic leukemia (ALL) cells and eliminates ALL stem/progenitor cells.Gene Expression Profiling of Ewing Sarcoma Tumors Reveals the Prognostic Importance of Tumor-Stromal Interactions: A Report from the Children's Oncology GroupPI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors.Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia.Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trialRNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications.Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemiaAn early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia studyAcute lymphoblastic leukemia relapsing after first-line pediatric-inspired therapy: a retrospective GRAALL study.Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement.Pediatric-like therapy for adults with ALL.Targeting the PI3K/mTOR Pathway in Pediatric Hematologic Malignancies.The challenge of targeting notch in hematologic malignancies.Current clinical regulation of PI3K/PTEN/Akt/mTOR signalling in treatment of human cancer.Pathogenesis and prognostication in acute lymphoblastic leukemia.Philadelphia chromosome-negative acute lymphoblastic leukemia: therapies under development.XI. Management of paediatric and adult non-Hodgkin lymphoma: what lessons can each teach the other?Outlook on PI3K/AKT/mTOR inhibition in acute leukemia.Oncogenic PTEN functions and models in T-cell malignancies.Driving Toward Precision Medicine for Acute Leukemias: Are We There Yet?Predictive value of (18)F-FDG PET/CT in adults with T-cell lymphoblastic lymphoma: post hoc analysis of results from the GRAALL-LYSA LLO3 trial.Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma.Current status and future directions of T-lymphoblastic lymphoma in children and adolescents.Targeting the mTOR Pathway in Leukemia.Microenvironmental cues for T-cell acute lymphoblastic leukemia development.Oncogenic Notch signaling in T-cell and B-cell lymphoproliferative disorders.Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activationRelapsed or Refractory Lymphoblastic Lymphoma in Children: Results and Analysis of 23 Patients in the EORTC 58951 and the LMT96 Protocols.Impact of conditioning with TBI in adult patients with T-cell ALL who receive a myeloablative allogeneic stem cell transplantation: a report from the acute leukemia working party of EBMT.Genetic mutational profiling analysis of T cell acute lymphoblastic leukemia reveal mutant FBXW7 as a prognostic indicator for inferior survival.NOTCH1 mutation, TP53 alteration and myeloid antigen expression predict outcome heterogeneity in children with first relapse of T-cell acute lymphoblastic leukemiaMeta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia.Suppression of T-cell lymphomagenesis in mice requires PTEN phosphatase activity.PI3Kγ/δ and NOTCH1 Cross-Regulate Pathways That Define the T-cell Acute Lymphoblastic Leukemia Disease Signature.Current challenges and opportunities in treating adult patients with Philadelphia-negative acute lymphoblastic leukaemia.
P2860
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P2860
Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
description
2013 nî lūn-bûn
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2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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name
Toward a NOTCH1/FBXW7/RAS/PTEN ...... Lymphoblastic Leukemia study.
@en
Toward a NOTCH1/FBXW7/RAS/PTEN ...... Lymphoblastic Leukemia study.
@nl
type
label
Toward a NOTCH1/FBXW7/RAS/PTEN ...... Lymphoblastic Leukemia study.
@en
Toward a NOTCH1/FBXW7/RAS/PTEN ...... Lymphoblastic Leukemia study.
@nl
prefLabel
Toward a NOTCH1/FBXW7/RAS/PTEN ...... Lymphoblastic Leukemia study.
@en
Toward a NOTCH1/FBXW7/RAS/PTEN ...... Lymphoblastic Leukemia study.
@nl
P2093
P50
P356
P1476
Toward a NOTCH1/FBXW7/RAS/PTEN ...... Lymphoblastic Leukemia study.
@en
P2093
Agnès Buzyn
Aline Tanguy-Schmidt
Amélie Trinquand
André Delannoy
Bertrand Nadel
Caroline Bonmati
Elizabeth Macintyre
Etienne Lengliné
Françoise Huguet
Hervé Dombret
P304
P356
10.1200/JCO.2012.48.5292
P407
P577
2013-10-28T00:00:00Z