Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes. - Wikidata - wikimedia - TriplyDB

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.

http://www.wikidata.org/entity/Q53085119

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Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease Fatty acid synthase cooperates with glyoxalase 1 to protect against sugar toxicity Progenitor cell dysfunctions underlie some diabetic complications Dietary Metabolites and Chronic Kidney Disease.Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease.Glyoxalase-1 overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hindlimb ligation model.Uremic Toxicity of Advanced Glycation End Products in CKD.Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage.Methylglyoxal and glyoxalase I in atherosclerosis.Glyoxalase I (Glo1) and its metabolites in vascular disease.Advanced glycation end product accumulation: a new enemy to target in chronic kidney disease?The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases.Effect of diet-derived advanced glycation end products on inflammation.Marein protects against methylglyoxal-induced apoptosis by activating the AMPK pathway in PC12 cells.RAGE and glyoxalase in kidney disease.Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers-A New Perspective?Methylglyoxal in Metabolic Disorders: Facts, Myths, and Promises.Glycative Stress and Its Defense Machinery Glyoxalase 1 in Renal Pathogenesis.Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention.Metabolic Regulation of Angiogenesis in Diabetes and Aging.A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice.Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates.NAD(+)-linked alcohol dehydrogenase 1 regulates methylglyoxal concentration in Candida albicans.Methylglyoxal-derived hydroimidazolone-1 evokes inflammatory reactions in endothelial cells via an interaction with receptor for advanced glycation end products.Activation of general control nonderepressible 2 kinase protects human glomerular endothelial cells from harmful high-glucose-induced molecular pathways.The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases.The acute-phase mediator serum amyloid A is associated with symptoms of depression and fatigue.Pathophysiology and therapeutics of premature ageing in chronic kidney disease, with a focus on glycative stress.Impact of intensive treatment on serum methylglyoxal levels among individuals with screen-detected type 2 diabetes: the ADDITION-Denmark study.Blood glucose fluctuation accelerates renal injury involved to inhibit the AKT signaling pathway in diabetic rats.Deleterious Effect of Advanced CKD on Glyoxalase System Activity not Limited to Diabetes Aetiology.1,25-Dihydroxyvitamin D increases the gene expression of enzymes protecting from glucolipotoxicity in peripheral blood mononuclear cells and human primary endothelial cells.Eucommia ulmoides Ameliorates Glucotoxicity by Suppressing Advanced Glycation End-Products in Diabetic Mice Kidney.Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice

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Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.

http://www.wikidata.org/entity/Q53085119

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Glyoxalase-1 overexpression re ...... nt in a rat model of diabetes.

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Glyoxalase-1 overexpression re ...... nt in a rat model of diabetes.

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Ben J A Janssen

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Carine J Peutz-Kootstra

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Michael Brownlee

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Olaf Brouwers

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Peter H Mundel

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Petra M G Niessen

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Toshio Miyata

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P2860

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

Biochemistry and molecular cell biology of diabetic complications

Hyperglycemia and microvascular and macrovascular disease in diabetes

The pathobiology of diabetic complications: a unifying mechanism

Mechanisms underlying endothelial dysfunction in diabetes mellitus.

Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment.

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

Role of adhesion molecules in vascular regulation and damage.

Nonenzymatic browning in vivo: possible process for aging of long-lived proteins.

The glyoxalase system in health and disease.

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Jo G. R. De Mey

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Jakob A Østergaard

Coenraad Dirk Adriaan Stehouwer

Casper G. Schalkwijk

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