Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance.
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Cytogenetic and molecular abnormalities in chronic myelomonocytic leukemiaClinical implications of U2AF1 mutation in patients with myelodysplastic syndrome and its stability during disease progression.Refractory anemia with ring sideroblasts and RARS with thrombocytosisMayo prognostic model for WHO-defined chronic myelomonocytic leukemia: ASXL1 and spliceosome component mutations and outcomes.Chronic myelomonocytic leukemia in younger patients: molecular and cytogenetic predictors of survival and treatment outcome.Mechanisms of genome instability induced by RNA-processing defects.Molecular genetics of chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia.Detection of SRSF2-P95 mutation by high-resolution melting curve analysis and its effect on prognosis in myelodysplastic syndrome.Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25CSpecific molecular signatures predict decitabine response in chronic myelomonocytic leukemia.Chronic myelomonocytic leukemia: Forefront of the field in 2015.Decitabine priming prior to low-dose chemotherapy improves patient outcomes in myelodysplastic syndromes-RAEB: a retrospective analysis vs. chemotherapy aloneRegulation of splicing by SR proteins and SR protein-specific kinases.Chronic myelomonocytic leukemia: 2013 update on diagnosis, risk stratification, and management.Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors.Splicing factor mutations and cancer.Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance.Splice factor mutations and alternative splicing as drivers of hematopoietic malignancy.Chronic Myelomonocytic Leukemia: a Genetic and Clinical Update.Diverse regulation of 3' splice site usage.Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.Chronic myelomonocytic leukemia: 2016 update on diagnosis, risk stratification, and management.Splicing factor gene mutations in hematologic malignancies.Genetic stratification in myeloid diseases: from risk assessment to clinical decision support tool.Refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis (RARS-T): 2017 update on diagnosis, risk-stratification, and management.DNMT3A mutations are associated with inferior overall and leukemia-free survival in chronic myelomonocytic leukemia.Predictors of survival in refractory anemia with ring sideroblasts and thrombocytosis (RARS-T) and the role of next-generation sequencing.The prognostic implication of SRSF2 mutations in Chinese patients with acute myeloid leukemia.Leukocytosis and presence of CALR mutation is associated with non-hepatosplenic extramedullary hematopoiesis in primary myelofibrosis.U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype.Driver mutations and prognosis in primary myelofibrosis: Mayo-Careggi MPN alliance study of 1,095 patients.Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.Insights from structures of cancer-relevant pre-mRNA splicing factors.Splicing Factor Mutations in Cancer.The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.Molecular and prognostic correlates of cytogenetic abnormalities in chronic myelomonocytic leukemia: a Mayo Clinic-French Consortium Study.Preferential occurrence of spliceosome mutations in acute myeloid leukemia with preceding myelodysplastic syndrome and/or myelodysplasia morphology.Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types.SRSF2 mutations in myelodysplasia/myeloproliferative neoplasmsBiallelic inactivation of the retinoblastoma gene results in transformation of chronic myelomonocytic leukemia to a blastic plasmacytoid dendritic cell neoplasm: shared clonal origins of two aggressive neoplasms
P2860
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P2860
Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Spliceosome mutations involvin ...... tes, and prognostic relevance.
@en
Spliceosome mutations involvin ...... tes, and prognostic relevance.
@nl
type
label
Spliceosome mutations involvin ...... tes, and prognostic relevance.
@en
Spliceosome mutations involvin ...... tes, and prognostic relevance.
@nl
prefLabel
Spliceosome mutations involvin ...... tes, and prognostic relevance.
@en
Spliceosome mutations involvin ...... tes, and prognostic relevance.
@nl
P2093
P2860
P356
P1476
Spliceosome mutations involvin ...... tes, and prognostic relevance.
@en
P2093
Animesh Pardanani
Christy M Finke
Curtis A Hanson
Janice M Hodnefield
Mrinal M Patnaik
Ryan A Knudson
Terra L Lasho
P2860
P304
P356
10.1002/AJH.23373
P577
2013-01-18T00:00:00Z