UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
about
The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia proteinPHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expressionModifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseSignalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancerAssociations of DNMT3B -149C>T and -2437T>A polymorphisms and lung cancer risk in Chinese populationDown-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer propertiesBilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway.Analysis of UHRF1 expression in human ovarian cancer tissues and its regulation in cancer cell growth.An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancerRFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylationUHRF1 promotes proliferation of gastric cancer via mediating tumor suppressor gene hypermethylation.Epigenetic mechanisms in anti-cancer actions of bioactive food components--the implications in cancer preventionQuantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer.A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choiceUHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesisUHRF1 overexpression is involved in cell proliferation and biochemical recurrence in prostate cancer after radical prostatectomyTPL2 kinase is a suppressor of lung carcinogenesisUHRF1 gene silencing inhibits cell proliferation and promotes cell apoptosis in human cervical squamous cell carcinoma CaSki cells.Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of "de novo" SCN1A Mutations in Children with Dravet Syndrome.Molecular gene signature and prognosis of non-small cell lung cancer.UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma.Zebrafish Discoveries in Cancer Epigenetics.Elevated UHRF1 expression contributes to poor prognosis by promoting cell proliferation and metastasis in hepatocellular carcinoma.CDDO-Me reveals USP7 as a novel target in ovarian cancer cells.The Roles of the Methyl-CpG Binding Proteins in Cancer.Inhibiting UHRF1 expression enhances radiosensitivity in human esophageal squamous cell carcinoma.Clinicopathological analysis of UHRF1 expression in medulloblastoma tissues and its regulation on tumor cell proliferation.Diagnostic and prognostic value of plasma and tissue ubiquitin-like, containing PHD and RING finger domains 1 in breast cancer patients.The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer.Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1.Analysis of the UHRF1 expression in serum and tissue for gastric cancer detection.Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients.Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts.L-methionase: a therapeutic enzyme to treat malignancies.Targeting microRNA/UHRF1 pathways as a novel strategy for cancer therapy.Overexpression of UHRF1 is significantly associated with poor prognosis in laryngeal squamous cell carcinoma.UHRF1 promotes cell growth and metastasis through repression of p16(ink⁴a) in colorectal cancer.Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL.LINE-1 hypomethylation is inversely correlated with UHRF1 overexpression in gastric cancer.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.
P2860
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P2860
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
@en
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
@nl
type
label
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
@en
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
@nl
prefLabel
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
@en
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
@nl
P2093
P2860
P50
P356
P1433
P1476
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer
@en
P2093
Alexandros Daskalos
George Nikolaidis
John R Gosney
Triantafillos Liloglou
P2860
P304
P356
10.1002/CNCR.25531
P407
P577
2010-11-08T00:00:00Z