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The lipid phosphatase activity of PTEN is critical for its tumor supressor functionThe tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal regionK-ras mutations appear in the premalignant phase of both microsatellite stable and unstable endometrial carcinogenesisAberrant hyperactivation of akt and Mammalian target of rapamycin complex 1 signaling in sporadic chordomasRegulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NF-kappaB/IkappaB pathwayMulti-organ Mapping of Cancer RiskThe estrogen receptor joins other cancer biomarkers as a predictor of outcomePTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancerRegion-specific transcriptional response to chronic nicotine in rat brainNovel germline mutations in the PTEN tumour suppressor gene found in women with multiple cancersMutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systemsNew insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathwayStructural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerbeta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus.Germline mutations and polymorphisms in the origins of cancers in women.Hypoxia-inducible factor-1 as a therapeutic target in endometrial cancer managementGermline PTEN mutations in Cowden syndrome-like families.Association between PTEN Gene IVS4 polymorphism and risk of cancer: a meta-analysisAllele-specific tumor spectrum in pten knockin miceExpression of the DMBT1 gene is frequently suppressed in human lung cancer.Controversies in the management of endometrial carcinoma.PTEN expression causes feedback upregulation of insulin receptor substrate 2The emerging genomic landscape of endometrial cancer.Prognostic significance of miR-205 in endometrial cancer.Loss of heterozygosity on 10q23.3 and mutation of tumor suppressor gene PTEN in gastric cancer and precancerous lesions.Inhibition of AKT with the orally active allosteric AKT inhibitor, MK-2206, sensitizes endometrial cancer cells to progestin.Visual gene-network analysis reveals the cancer gene co-expression in human endometrial cancerIndole-3-carbinol prevents PTEN loss in cervical cancer in vivoPathologic scoring of PTEN immunohistochemistry in endometrial carcinoma is highly reproducibleThe PTEN/NRF2 axis promotes human carcinogenesisGenetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instabilityEndometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study.Gene expression analysis of early stage endometrial cancers reveals unique transcripts associated with grade and histology but not depth of invasion.Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management.Negative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing FieldAdenovirus mediated homozygous endometrial epithelial Pten deletion results in aggressive endometrial carcinoma.Progesterone receptor-B induction of BIRC3 protects endometrial cancer cells from AP1-59-mediated apoptosis.Krüppel-like factor 9 loss-of-expression in human endometrial carcinoma links altered expression of growth-regulatory genes with aberrant proliferative response to estrogen.The KRAS-variant and miRNA expression in RTOG endometrial cancer clinical trials 9708 and 9905Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
PTEN/MMAC1 mutations in endometrial cancers.
@en
PTEN/MMAC1 mutations in endometrial cancers.
@nl
type
label
PTEN/MMAC1 mutations in endometrial cancers.
@en
PTEN/MMAC1 mutations in endometrial cancers.
@nl
prefLabel
PTEN/MMAC1 mutations in endometrial cancers.
@en
PTEN/MMAC1 mutations in endometrial cancers.
@nl
P2093
P1433
P1476
PTEN/MMAC1 mutations in endometrial cancers
@en
P2093
Barrett JC
Berchuck A
Risinger JI
P304
P407
P577
1997-11-01T00:00:00Z