Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.
about
The characterization of a mammalian DNA structure-specific endonucleaseMolecular basis of the cell-surface expression of immunoglobulin mu chain without light chain in human B lymphocytesRegulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zetaThe XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinaseDefective DNA repair and increased genomic instability in Artemis-deficient murine cellsPhospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cellsDevelopment of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathwayUtilization of oriented peptide libraries to identify substrate motifs selected by ATM.Wortmannin potentiates integrase-mediated killing of lymphocytes and reduces the efficiency of stable transduction by retroviruses.Computational analysis of retrovirus-induced scid cell death.Characterization of retrovirus-host DNA junctions in cells deficient in nonhomologous-end joiningIsolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joinsT-cell receptor gene rearrangements in functional T-cell clones from severe combined immune deficient (scid) mice: reversion of the scid phenotype in individual lymphocyte progenitors.The actin-binding protein caldesmon is in spleen and lymph nodes predominately expressed by smooth-muscle cells, reticular cells, and follicular dendritic cells.Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.Animal systems for translational research in radiation oncology.Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus.Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase.Development of pemphigus vulgaris-like lesions in severe combined immunodeficiency disease mice reconstituted with lymphocytes from patients.V(D)J recombination activity in lymphoid cell lines is increased by agents that elevate cAMPIrradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.Role of CD4+, CD8+ and double negative T-cells in the protection of SCID/beige mice against respiratory challenge with Rhodococcus equi.Evidence for failure of V(D)J recombination in bone marrow pre-B cells from X-linked agammaglobulinemia.Severe combined immunodeficiency mouse-human skin chimeras: a unique animal model for the study of psoriasis and cutaneous inflammation.New animal models of hepatitis B and C.Murine "viable motheaten" mutation reveals a gene critical to the development of both B and T lymphocytesUse of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity.Ku-dependent and Ku-independent end-joining pathways lead to chromosomal rearrangements during double-strand break repair in Saccharomyces cerevisiae.High rates of deletions in the constant region segment of the immunoglobulin mu gene.The molecular mechanism underlying formation of deletions in Fanconi anemia cells may involve a site-specific recombinationComplementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen.Spontaneous nonthymic tumors in SCID mice.Premature termination of variable gene rearrangement in B lymphocytes from X-linked agammaglobulinemia.Differential effect of an Ig mu transgene on development of pre-B cells in fetal and adult SCID mice.Induction of lung fibrosis in the mouse by intratracheal instillation of fluorescein isothiocyanate is not T-cell-dependentSpontaneous Pneumocystis carinii pneumonia in immunodeficient mutant scid mice. Natural history and pathobiologyControl of human B cell tumor growth in severe combined immunodeficiency mice by monoclonal anti-B cell antibodies.Hemagglutination and graft-versus-host disease in the severe combined immunodeficiency mouse lymphoproliferative disease modelCharacterization of hu-PBL-SCID mice with high human immunoglobulin serum levels and graft-versus-host disease.
P2860
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P2860
Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh-hant
name
Rearrangement of antigen recep ...... re combined immune deficiency.
@en
Rearrangement of antigen recep ...... re combined immune deficiency.
@nl
type
label
Rearrangement of antigen recep ...... re combined immune deficiency.
@en
Rearrangement of antigen recep ...... re combined immune deficiency.
@nl
prefLabel
Rearrangement of antigen recep ...... re combined immune deficiency.
@en
Rearrangement of antigen recep ...... re combined immune deficiency.
@nl
P2093
P1433
P1476
Rearrangement of antigen recep ...... re combined immune deficiency.
@en
P2093
I J Weiler
J F Kearney
N Rosenberg
R A Phillips
P304
P356
10.1016/0092-8674(86)90695-1
P407
P577
1986-09-01T00:00:00Z