Inhibition of colon cancer (HT-29) cell proliferation by a triterpenoid isolated from Azadirachta indica is accompanied by cell cycle arrest and up-regulation of p21.
about
Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its developmentNeem components as potential agents for cancer prevention and treatmentReview on molecular and chemopreventive potential of nimbolide in cancerNimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironmentPrevention and Treatment of Colorectal Cancer by Natural Agents From Mother Nature.Inhibition of cell survival and proliferation by nimbolide in human androgen-independent prostate cancer (PC-3) cells: involvement of the PI3K/Akt pathway.Induction of cell cycle arrest, DNA damage, and apoptosis by nimbolide in human renal cell carcinoma cells.Nimbolide inhibits IGF-I-mediated PI3K/Akt and MAPK signalling in human breast cancer cell lines (MCF-7 and MDA-MB-231).Direct inhibition of retinoblastoma phosphorylation by nimbolide causes cell-cycle arrest and suppresses glioblastoma growth.Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-κB in colon cancer cells.The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells.Nimbolide a limonoid from Azadirachta indica inhibits proliferation and induces apoptosis of human choriocarcinoma (BeWo) cells.Azadirachta indica acts as a pro-oxidant and modulates cell cycle associated proteins during DMBA/TPA induced skin carcinogenesis in mice.Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic cancer cells.
P2860
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P2860
Inhibition of colon cancer (HT-29) cell proliferation by a triterpenoid isolated from Azadirachta indica is accompanied by cell cycle arrest and up-regulation of p21.
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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2006年學術文章
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2006年學術文章
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name
Inhibition of colon cancer (HT ...... rest and up-regulation of p21.
@en
Inhibition of colon cancer
@nl
type
label
Inhibition of colon cancer (HT ...... rest and up-regulation of p21.
@en
Inhibition of colon cancer
@nl
prefLabel
Inhibition of colon cancer (HT ...... rest and up-regulation of p21.
@en
Inhibition of colon cancer
@nl
P2093
P356
P1433
P1476
Inhibition of colon cancer (HT ...... rest and up-regulation of p21.
@en
P2093
Hiroshi Shinmoto
Kazuhiko Nakahara
Makiko Takenaka
Masuko Kobori
Molay Kumar Roy
Tojiro Tsushida
P304
P356
10.1055/S-2006-946694
P577
2006-07-20T00:00:00Z