Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy.
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Anogenital distance in human male and female newborns: a descriptive, cross-sectional studyCumulative effects of in utero administration of mixtures of reproductive toxicants that disrupt common target tissues via diverse mechanisms of toxicityAltered gene expression during rat Wolffian duct development in response to in utero exposure to the antiandrogen linuronDipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates.Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidismWidely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens.The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses: phase 2 dose-response studies.Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals.Evaluation of the estrogenic activity of Indian medicinal plants in immature ratsIn utero exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin affects the development of reproductive system in mouse.Diverse mechanisms of anti-androgen action: impact on male rat reproductive tract development.Cumulative effects of in utero administration of mixtures of "antiandrogens" on male rat reproductive development.Proliferative and nonproliferative lesions of the rat and mouse male reproductive system.Maternal linuron exposure alters testicular development in male offspring rats at the whole genome level.Generational reproductive outcomes in Wistar rats maternally exposed to Ricinus communis oil at different stages of gestation.Comparison of linuron degradation in the presence of pesticide mixtures in soil under laboratory conditions.Functional and morphological reproductive aspects in male rats exposed to di-n-butyl phthalate (DBP) in utero and during lactation.Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat.Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate.Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis.Mixtures of endocrine disrupting contaminants modelled on human high end exposures: an exploratory study in rats.Reproductive disorders in female rats after prenatal exposure to betamethasone.Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A.Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat.Influence of Study Design on Developmental and Reproductive Toxicology Study Outcomes.Perinatal exposure to androgen excess and the effects on the rat uterine estradiol responsiveness.Maternal exposure to butyl paraben impairs testicular structure and sperm quality on male rats.Long-term effects of in utero and lactational exposure to butyl paraben in female rats.An extended one-generation reproductive toxicity test of 1,2,4-Triazol-5-one (NTO) in rats.Effects of diuron on male rat reproductive organs: a developmental and postnatal study.Anogenital distance in male and female fetuses at 20 to 35 weeks of gestation: centile charts and reference ranges.Perinatal androgenic exposure and reproductive health effects female rat offspring.
P2860
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P2860
Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy.
description
2002 nî lūn-bûn
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2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
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2002年學術文章
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2002年學術文章
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name
Male rats exposed to linuron i ...... subsequent testicular atrophy.
@en
Male rats exposed to linuron i ...... subsequent testicular atrophy.
@nl
type
label
Male rats exposed to linuron i ...... subsequent testicular atrophy.
@en
Male rats exposed to linuron i ...... subsequent testicular atrophy.
@nl
prefLabel
Male rats exposed to linuron i ...... subsequent testicular atrophy.
@en
Male rats exposed to linuron i ...... subsequent testicular atrophy.
@nl
P2093
P356
P1476
Male rats exposed to linuron i ...... subsequent testicular atrophy.
@en
P2093
Barry S McIntyre
Norman J Barlow
Paul M D Foster
P356
10.1093/TOXSCI/65.1.62
P577
2002-01-01T00:00:00Z