SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway. - Wikidata - wikimedia - TriplyDB

SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.

SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.

http://www.wikidata.org/entity/Q53959197

about

Akt and mTOR in B Cell Activation and Differentiation Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2 Foxo3a: an integrator of immune dysfunction during HIV infection Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling A Conditional Knockout Mouse Model Reveals That Calponin-3 Is Dispensable for Early B Cell Development Signaling by the phosphoinositide 3-kinase family in immune cells The transmembrane adaptor protein SIT inhibits TCR-mediated signaling The adaptor protein Shc plays a key role during early B cell development Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL.Arginine methylation of the B cell antigen receptor promotes differentiation.Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.B lymphocyte lineage specification, commitment and epigenetic control of transcription by early B cell factor 1.Highly specialized role of Forkhead box O transcription factors in the immune system.miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions.Rictor is required for early B cell development in bone marrow.Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC.Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia PI3Ks in lymphocyte signaling and development NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity Integrated signaling in developing lymphocytes: the role of DNA damage responses.PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.Lymphocyte development: integration of DNA damage response signaling.RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes Mechanisms controlling expression of the RAG locus during lymphocyte development.Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation Foxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell sub-population distribution.A C-terminal acidic domain regulates degradation of the transcriptional coactivator Bob1.Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals Balancing Proliferation with Igκ Recombination during B-lymphopoiesis Ikaros in immune receptor signaling, lymphocyte differentiation, and function.Perspectives on the role of mTORC2 in B lymphocyte development, immunity and tumorigenesis.Lymphocyte signaling: regulation of FoxO transcription factors by microRNAs.Transcriptional control of early T and B cell developmental choices Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia.

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P2860

SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.

http://www.wikidata.org/entity/Q53959197

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

@zh-hant

name

SLP-65 regulates immunoglobulin light chain gene recombination through the PI

@nl

SLP-65 regulates immunoglobuli ...... h the PI(3)K-PKB-Foxo pathway.

@en

type

label

SLP-65 regulates immunoglobulin light chain gene recombination through the PI

@nl

SLP-65 regulates immunoglobuli ...... h the PI(3)K-PKB-Foxo pathway.

@en

prefLabel

SLP-65 regulates immunoglobulin light chain gene recombination through the PI

@nl

SLP-65 regulates immunoglobuli ...... h the PI(3)K-PKB-Foxo pathway.

@en

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P1433

Nature Immunology

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SLP-65 regulates immunoglobuli ...... gh the PI(3)K-PKB-Foxo pathway

@en

P2093

Eva Hug

http://www.w3.org/2001/XMLSchema#string

Hassan Jumaa

http://www.w3.org/2001/XMLSchema#string

Ji-Hye Paik

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Michael Reth

http://www.w3.org/2001/XMLSchema#string

Ronald A DePinho

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Sonja Meixlsperger

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P2860

Direct control of the Forkhead transcription factor AFX by protein kinase B

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells.

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

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623-631

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10.1038/NI.1616

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P433

6

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9

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Sebastian Herzog

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2008-06-01T00:00:00Z

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18488031

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