Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani. - Wikidata - wikimedia - TriplyDB

Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.

Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.

http://www.wikidata.org/entity/Q54027189

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Leishmania TDR1 structure, a unique trimeric glutathione transferase capable of deglutathionylation and antimonial prodrug activation New Approaches to Overcome Transport Related Drug Resistance in Trypanosomatid Parasites Pentavalent antimonials: new perspectives for old drugs Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential Unresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drug-resistant Leishmania tropica parasites.Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensis Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant Quinone-amino acid conjugates targeting Leishmania amino acid transporters Intrachromosomal amplification, locus deletion and point mutation in the aquaglyceroporin AQP1 gene in antimony resistant Leishmania (Viannia) guyanensis Species-specific antimonial sensitivity in Leishmania is driven by post-transcriptional regulation of AQP1 Drug resistance in leishmaniasis Drug resistance in eukaryotic microorganisms.Microbial Antimony Biogeochemistry: Enzymes, Regulation, and Related Metabolic Pathways.Antimony transport mechanisms in resistant leishmania parasites.Efficacies of vesicular and free sodium stibogluconate formulations against clinical isolates of Leishmania donovani Molecular biological applications in the diagnosis and control of leishmaniasis and parasite identification.The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis Sb(V) reactivity with human blood components: redox effects A novel marker, ARM58, confers antimony resistance to Leishmania spp Use of antimony in the treatment of leishmaniasis: current status and future directions.Antimony resistance in leishmania, focusing on experimental research.Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation Antimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimony-resistant parasites Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony New delivery strategies for the old pentavalent antimonial drugs.ABC transporters involved in drug resistance in human parasites.Hyphenated techniques as tools for speciation analysis of metal-based pharmaceuticals: developments and applications.Reduced antimony accumulation in ARM58-overexpressing Leishmania infantum.Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes.Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum.Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art.Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal.Chemotherapy of leishmaniasis: present challenges.Reduction of Sb(V) in a human macrophage cell line measured by HPLC-ICP-MS.Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays.Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonials Profiling gene expression of antimony response genes in Leishmania (Viannia) panamensis and infected macrophages and its relationship with drug susceptibility.Nanostructured delivery systems with improved leishmanicidal activity: a critical review.

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P2860

Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.

http://www.wikidata.org/entity/Q54027189

description

2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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Novel Intracellular SbV reduci ...... bility in Leishmania donovani.

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Novel Intracellular SbV reduci ...... bility in Leishmania donovani.

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Novel Intracellular SbV reduci ...... bility in Leishmania donovani.

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Novel Intracellular SbV reduci ...... bility in Leishmania donovani.

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Novel Intracellular SbV reduci ...... bility in Leishmania donovani.

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Ephros M

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Shaked-Mishan P

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Ulrich N

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Zilberstein D

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P2860

Ligand interactions of the ArsC arsenate reductase.

Antileishmanial activity of sodium stibogluconate fractions.

Cloning and characterization of differentially expressed genes from in vitro-grown 'amastigotes' of Leishmania donovani.

An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae.

In vitro antileishmanial properties of tri- and pentavalent antimonial preparations.

Biochemical mechanisms of the antileishmanial activity of sodium stibogluconate.

New mechanisms of drug resistance in parasitic protozoa.

Resistance mechanisms to arsenicals and antimonials.

Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae.

Pentamidine uptake in Leishmania donovani and Leishmania amazonensis promastigotes and axenic amastigotes.

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3971-3976

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scholarly article

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10.1074/JBC.M005423200

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6

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276

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11110784

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