Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.
about
Leishmania TDR1 structure, a unique trimeric glutathione transferase capable of deglutathionylation and antimonial prodrug activationNew Approaches to Overcome Transport Related Drug Resistance in Trypanosomatid ParasitesPentavalent antimonials: new perspectives for old drugsDual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovaniArsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potentialUnresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drug-resistant Leishmania tropica parasites.Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensisProteomic and genomic analyses of antimony resistant Leishmania infantum mutantQuinone-amino acid conjugates targeting Leishmania amino acid transportersIntrachromosomal amplification, locus deletion and point mutation in the aquaglyceroporin AQP1 gene in antimony resistant Leishmania (Viannia) guyanensisSpecies-specific antimonial sensitivity in Leishmania is driven by post-transcriptional regulation of AQP1Drug resistance in leishmaniasisDrug resistance in eukaryotic microorganisms.Microbial Antimony Biogeochemistry: Enzymes, Regulation, and Related Metabolic Pathways.Antimony transport mechanisms in resistant leishmania parasites.Efficacies of vesicular and free sodium stibogluconate formulations against clinical isolates of Leishmania donovaniMolecular biological applications in the diagnosis and control of leishmaniasis and parasite identification.The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesisSb(V) reactivity with human blood components: redox effectsA novel marker, ARM58, confers antimony resistance to Leishmania sppUse of antimony in the treatment of leishmaniasis: current status and future directions.Antimony resistance in leishmania, focusing on experimental research.Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiationAntimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimony-resistant parasitesIncreased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimonyNew delivery strategies for the old pentavalent antimonial drugs.ABC transporters involved in drug resistance in human parasites.Hyphenated techniques as tools for speciation analysis of metal-based pharmaceuticals: developments and applications.Reduced antimony accumulation in ARM58-overexpressing Leishmania infantum.Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes.Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum.Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art.Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal.Chemotherapy of leishmaniasis: present challenges.Reduction of Sb(V) in a human macrophage cell line measured by HPLC-ICP-MS.Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays.Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonialsProfiling gene expression of antimony response genes in Leishmania (Viannia) panamensis and infected macrophages and its relationship with drug susceptibility.Nanostructured delivery systems with improved leishmanicidal activity: a critical review.
P2860
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P2860
Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
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@yue
2000年學術文章
@zh-hant
name
Novel Intracellular SbV reduci ...... bility in Leishmania donovani.
@en
Novel Intracellular SbV reduci ...... bility in Leishmania donovani.
@nl
type
label
Novel Intracellular SbV reduci ...... bility in Leishmania donovani.
@en
Novel Intracellular SbV reduci ...... bility in Leishmania donovani.
@nl
prefLabel
Novel Intracellular SbV reduci ...... bility in Leishmania donovani.
@en
Novel Intracellular SbV reduci ...... bility in Leishmania donovani.
@nl
P2093
P2860
P356
P1476
Novel Intracellular SbV reduci ...... bility in Leishmania donovani.
@en
P2093
Shaked-Mishan P
Zilberstein D
P2860
P304
P356
10.1074/JBC.M005423200
P407
P577
2000-11-10T00:00:00Z