Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.

Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.

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http://www.wikidata.org/entity/Q54104127
Mechanisms of HIV protein degradation into epitopes: implications for vaccine designSwapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidaseMajor histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidaseIdentification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-angiotensin type 1 (non-AT1), non-AT2 angiotensin binding siteFree ATP inhibits thimet oligopeptidase (EC 3.4.24.15) activity, induces autophosphorylation in vitro, and controls oligopeptide degradation in macrophage.The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor bindingComparative fine structural distribution of endopeptidase 24.15 (EC3.4.24.15) and 24.16 (EC3.4.24.16) in rat brain.Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selectionAnalysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells.Regulation of cell-surface major histocompatibility complex class I expression by the endopeptidase EC3.4.24.15 (thimet oligopeptidase).Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase.14-3-3 epsilon modulates the stimulated secretion of endopeptidase 24.15.ACE gene titration in mice uncovers a new mechanism for ACE on the control of body weight.Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE).Inhibition of thimet oligopeptidase by siRNA alters specific intracellular peptides and potentiates isoproterenol signal transduction.Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
P2860

Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.

Item
http://www.wikidata.org/entity/Q54104127
description
1999 nî lūn-bûn
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1999年の論文
@ja
1999年学术文章
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1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
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1999年學術文章
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name
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.
@en
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.
@nl
type
label
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.
@en
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.
@nl
prefLabel
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.
@en
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921