Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase
about
sameAs
Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidasesMechanisms of HIV protein degradation into epitopes: implications for vaccine designSwapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidaseThe ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residuesCrystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localizationIdentification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-angiotensin type 1 (non-AT1), non-AT2 angiotensin binding siteIdentification of an alternate splice form of tapasin in human melanoma.CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitopeDiscovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis.The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor bindingPuromycin-sensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradationThe internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1.PA28αβ: the enigmatic magic ring of the proteasome?Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes.Mapping sequence differences between thimet oligopeptidase and neurolysin implicates key residues in substrate recognition.Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme.Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagyVariable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape.Recycling of the high valence States of heme proteins by cysteine residues of THIMET-oligopeptidase.Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infectionThe cytoplasmic domain of rhesus cytomegalovirus Rh178 interrupts translation of major histocompatibility class I leader peptide-containing proteins prior to translocation.Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII.Post-proteasomal antigen processing for major histocompatibility complex class I presentation.The processing of antigens delivered as DNA vaccines.Analysis of the Yeast Peptidome and Comparison with the Human Peptidome.Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation.MHC class I alleles and their exploration of the antigen-processing machinery.Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cellsPeptidases released by necrotic cells control CD8+ T cell cross-priming.Insights into the processing of MHC class I ligands gained from the study of human tumor epitopes.Immunogenicity of necrotic cell death.Diverse HLA-I Peptide Repertoires of the APC Lines MUTZ3-Derived Immature and Mature Dendritic Cells and THP1-Derived Macrophages.β-Turn sequences promote stability of peptide substrates for kinases within the cytosolic environment.Using protease inhibitors in antigen presentation assays.Production of an antigenic peptide by insulin-degrading enzyme.The Caenorhabditis elegans orthologue of mammalian puromycin-sensitive aminopeptidase has roles in embryogenesis and reproduction.The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides.Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells.Varied Role of Ubiquitylation in Generating MHC Class I Peptide Ligands.
P2860
Q24304359-D40490EF-4C35-4C9A-B811-B95C7B9079F6Q26866505-98477ABB-B312-49DA-AA2D-E0BE3C4AA4F9Q27643647-032C6AB9-19CC-40D2-BB5C-AFE21A978BC7Q28115737-81A02B93-D600-402B-8CBA-B121C080D8D6Q28248182-A4864C1A-A41E-4E1B-AD0A-BD837D916A8DQ28586322-BA599606-D7CC-45EF-AB02-D3D040471544Q30156803-882092A9-6D61-4895-9686-6215C0F13B4DQ31010282-D1B089A3-D6B0-43B6-A1CD-71FB32DDC973Q31158745-D32E9E86-793E-4F8D-99C0-3C8B5F1C9793Q33274869-9130FBE0-FEC9-4529-A5B1-B704E6F36F87Q33275164-C079F630-E59D-4A3C-990A-268E7FF69FE9Q33382992-0EA90C05-2C4B-405F-BED3-91EF3D3C04A7Q33912635-CA36EE23-0B04-4FF0-BB6B-19FB203447A4Q34088438-2B941FF5-7EB7-40EB-8F9E-26727556705CQ34145666-73004DF3-E6AA-4CC2-BA4E-1F03E006A3F1Q34167013-6935511C-1299-4185-B252-B9C648DD7A60Q34275664-8CF72647-8B2E-4F49-B549-A45422F3E054Q35015691-19B21829-AAC1-49C8-89A2-9395D4B1936CQ35041150-4C90D1C8-14D8-4DB1-8886-9D8AD1588340Q35131219-0EBCFAE6-9A7F-4637-88E5-67D6348958C1Q35192920-D4888EB6-15E6-433A-8187-EF8506BA2DDAQ35821221-D42A0A21-D746-4031-901C-C81FC6077F72Q35821228-B54E306D-7A94-4A73-8BB4-653C48AEC27AQ35826365-15F29EDF-899E-485E-A621-77BB19B71298Q36148489-53BA0717-4621-4F49-90F2-8F0B2C64441DQ36266433-E5010538-4B46-442C-8525-67ED08ECE7F0Q36266437-1F3681AE-6575-41EC-A5CC-E488F490B417Q36399423-250E26B8-B89A-4B5A-B058-9B940A491162Q37162792-4A5BE159-3A05-425E-8741-12E1A94C45B4Q37259198-C28C5547-E38D-4C95-9C6C-39C2471040CDQ37851050-157A1512-6A21-4947-9D61-1581572F9DCBQ38255959-A99E9EE2-CFD6-4C47-ACBC-8AB26EDA2B03Q38750956-66E7EBB6-DF8B-43BF-80A7-AC74C70CE720Q39137252-BA0B472F-5691-48C1-98D2-78E8FE246ECCQ39208728-6D2CFF6F-1AD7-48C3-9FD0-DEA1134B46B4Q39719024-F37B841F-3ED5-4626-AEF4-10A5BC25BFC1Q39750868-E9D99F95-E40D-4802-9CF5-DBB3841819EFQ39814591-F1C013BC-BBC1-4EEA-9F8D-9B068818A564Q39873730-2DB9766B-F4A7-470D-8C40-FA2567AB1FBEQ40264818-6C3CD89E-AA46-4CD7-B6F9-2C8C4D268312
P2860
Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Major histocompatibility compl ...... arily by thimet oligopeptidase
@ast
Major histocompatibility compl ...... arily by thimet oligopeptidase
@en
Major histocompatibility compl ...... arily by thimet oligopeptidase
@nl
type
label
Major histocompatibility compl ...... arily by thimet oligopeptidase
@ast
Major histocompatibility compl ...... arily by thimet oligopeptidase
@en
Major histocompatibility compl ...... arily by thimet oligopeptidase
@nl
prefLabel
Major histocompatibility compl ...... arily by thimet oligopeptidase
@ast
Major histocompatibility compl ...... arily by thimet oligopeptidase
@en
Major histocompatibility compl ...... arily by thimet oligopeptidase
@nl
P2093
P2860
P3181
P356
P1476
Major histocompatibility compl ...... arily by thimet oligopeptidase
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M105517200
P407
P577
2001-09-28T00:00:00Z