about
Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcriptionCell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosisIAPs: a central element in the NF-κB activating signaling pathwayIAP proteins as targets for drug development in oncologyThe Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular StressRegulation of Apoptosis by Inhibitors of Apoptosis (IAPs)IAPs and cell migration.Towards the elaboration of new gold-based optical theranostics.Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein.DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues.The role of apoptosis in the pathogenesis and treatment of diseases.cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation.Regulation of E2F1 Transcription Factor by Ubiquitin Conjugation.E2F1 interacts with BCL-xL and regulates its subcellular localization dynamics to trigger cell death.IAPs: Mediators of Oncogenesis and Targets for Anticancer Therapy.Cellular pharmacology of azatoxins (topoisomerase-II and tubulin inhibitors) in P-glycoprotein-positive and -negative cell lines.E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin bindingHSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells[Apoptosis of human leukemic cells induced by topoisomerase I and II inhibitors]Increased gadd153 messenger RNA level is associated with apoptosis in human leukemic cells treated with etoposideBCR-ABL delays apoptosis upstream of procaspase-3 activationInhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines[IAP and Rho finally connected]Heat-shock proteins: chaperoning DNA repairSelecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapySerpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia[Unexpected role of IAPs in transcriptional regulation]IAP-Mediated Protein Ubiquitination in Regulating Cell Signaling
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description
onderzoeker
@nl
researcher
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հետազոտող
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name
L Dubrez
@ast
L Dubrez
@en
L Dubrez
@es
L Dubrez
@nl
L Dubrez
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type
label
L Dubrez
@ast
L Dubrez
@en
L Dubrez
@es
L Dubrez
@nl
L Dubrez
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prefLabel
L Dubrez
@ast
L Dubrez
@en
L Dubrez
@es
L Dubrez
@nl
L Dubrez
@sl
P106
P31
P496
0000-0002-7030-2181