Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling.
about
Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortexPhosphorylation of human pleckstrin on Ser-113 and Ser-117 by protein kinase CPhosphoinositol lipids bind to phosphatidylinositol 3 (PI3)-kinase enhancer GTPase and mediate its stimulatory effect on PI3-kinase and Akt signalingsThe solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunitsThe third intracellular domain of the platelet-activating factor receptor is a critical determinant in receptor coupling to phosphoinositide phospholipase C-activating G proteins. Studies using intracellular domain minigenes and receptor chimerasG protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasisStructural features of heterotrimeric G-protein-coupled receptors and their modulatory proteins.G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP.G protein beta gamma subunits stimulate phosphorylation of Shc adapter proteinA genetically encoded tool kit for manipulating and monitoring membrane phosphatidylinositol 4,5-bisphosphate in intact cells.G protein regulation of MAPK networks.Antisense oligonucleotides against receptor kinase GRK2 disrupt target selectivity of beta-adrenergic receptors in atrial myocytes.A dominant-negative strategy for studying roles of G proteins in vivo.The basal subcellular distribution of beta-adrenergic receptor kinase is independent of G-protein beta gamma subunits.Differential regulation of G-protein-mediated signaling by chemokine receptors.A phosphoinositide-binding sequence is shared by PH domain target molecules--a model for the binding of PH domains to proteins.The Ras/p120 GTPase-activating protein (GAP) interaction is regulated by the p120 GAP pleckstrin homology domain.The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting.IRS-1 mediates inhibition of Ca2+ mobilization by insulin via the inhibitory G-protein Gi.Isolated Sos1 PH domain exhibits germinal vesicle breakdown-inducing activity in Xenopus oocytes.Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells.
P2860
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P2860
Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling.
description
1995 nî lūn-bûn
@nan
1995年の論文
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1995年学术文章
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1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
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1995年學術文章
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1995年學術文章
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name
Effect of cellular expression ...... Gi-coupled receptor signaling.
@en
Effect of cellular expression ...... Gi-coupled receptor signaling.
@nl
type
label
Effect of cellular expression ...... Gi-coupled receptor signaling.
@en
Effect of cellular expression ...... Gi-coupled receptor signaling.
@nl
prefLabel
Effect of cellular expression ...... Gi-coupled receptor signaling.
@en
Effect of cellular expression ...... Gi-coupled receptor signaling.
@nl
P2093
P2860
P356
P1476
Effect of cellular expression ...... Gi-coupled receptor signaling
@en
P2093
R J Lefkowitz
T van Biesen
P2860
P304
12984-12989
P356
10.1074/JBC.270.22.12984
P407
P577
1995-06-01T00:00:00Z