A common sequence motif associated with recombination hot spots and genome instability in humans
about
Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general populationMechanisms of change in gene copy numberVariants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populationsPRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humansGenome-wide analysis reveals novel molecular features of mouse recombination hotspotsA map of human genome variation from population-scale sequencingNucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint libraryMechanisms underlying structural variant formation in genomic disordersNew paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombinationMultiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNAWhat determines the localisation of spots of meiotic recombination?DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombinationGenetic analysis of genome-scale recombination rate evolution in house miceProbing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencingStructures and molecular mechanisms for common 15q13.3 microduplications involving CHRNA7: benign or pathological?Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombinationOrigins and functional impact of copy number variation in the human genomeSubstitution patterns are under different influences in primates and rodentsCharacterization of the past and current duplication activities in the human 22q11.2 regionPrdm9, a major determinant of meiotic recombination hotspots, is not functional in dogs and their wild relatives, wolves and coyotesVariation in human recombination rates and its genetic determinantsCopy number variation, chromosome rearrangement, and their association with recombination during avian evolutionThe recombination landscape of the zebra finch Taeniopygia guttata genomeMolecular evolution of genes in avian genomesIntegration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data AnalysisDistribution of recombination hotspots in the human genome--a comparison of computer simulations with real dataCharacterizing complex structural variation in germline and somatic genomesThe landscape of recombination in African Americans.Genome-wide mapping and assembly of structural variant breakpoints in the mouse genomeAlu repeats increase local recombination rates.Diversity of Prdm9 zinc finger array in wild mice unravels new facets of the evolutionary turnover of this coding minisatelliteGenome-wide control of the distribution of meiotic recombinationTrans-regulation of mouse meiotic recombination hotspots by Rcr1.Novel nucleotide sequence motifs that produce hotspots of meiotic recombination in Schizosaccharomyces pombe.The new yeast is a mouse.Anatomy of mouse recombination hot spotsGenetic crossovers are predicted accurately by the computed human recombination mapRecombinational landscape of porcine X chromosome and individual variation in female meiotic recombination associated with haplotypes of Chinese pigs.The 8p23 inversion polymorphism determines local recombination heterogeneity across human populationsRefined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
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P2860
A common sequence motif associated with recombination hot spots and genome instability in humans
description
im August 2008 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 2008
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name
A common sequence motif associ ...... d genome instability in humans
@en
A common sequence motif associ ...... d genome instability in humans
@nl
type
label
A common sequence motif associ ...... d genome instability in humans
@en
A common sequence motif associ ...... d genome instability in humans
@nl
prefLabel
A common sequence motif associ ...... d genome instability in humans
@en
A common sequence motif associ ...... d genome instability in humans
@nl
P2093
P2860
P356
P1433
P1476
A common sequence motif associ ...... d genome instability in humans
@en
P2093
Adam Auton
Colin Freeman
Gil McVean
P2860
P2888
P304
P356
10.1038/NG.213
P407
P577
2008-08-24T00:00:00Z