Genetic dissection of autoimmune type I diabetes in the BB rat.
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Common genetic determinants of uveitis shared with other autoimmune disordersConstruction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetesGenetic dissection of complex genetic factor involved in NIDDM of OLETF ratExpression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP-binding motifsTransgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the ratHigh-throughput gene discovery in the rat.Three-color cDNA microarrays with prehybridization quality control yield gene expression data comparable to that of commercial platforms.The iddm4 locus segregates with diabetes susceptibility in congenic WF.iddm4 rats.Biobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes.Rat Genome Database (RGD): mapping disease onto the genomeIdentification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward geneticsEvidence for the presence of insulin-dependent diabetes-associated alleles on the distal part of mouse chromosome 6.Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system?Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells.Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the ratLymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.Rat models of type 1 diabetes: genetics, environment, and autoimmunity.Thymic epithelial defects and predisposition to autoimmune disease in BB rats.Lupus susceptibility loci in New Zealand mice.Innate inflammation in type 1 diabetesUtility of murine models for the study of spontaneous autoimmune type 1 diabetes.Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases.A major histocompatibility complex class II restriction for BioBreeding/Worcester diabetes-inducing T cells.NPY and NPY receptors in airway structural and inflammatory cells in allergic asthma.CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor rats.Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j miceGenetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia geneForward and reverse genetic approaches to behavior in the mouse.Evidence for oligogenic inheritance of type 1 diabetes in a large Bedouin Arab family.Longitudinal analysis of hepatic transcriptome and serum metabolome demonstrates altered lipid metabolism following the onset of hyperglycemia in spontaneously diabetic biobreeding rats.Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.Gimap and T cells: a matter of life or death.A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes.A non-MHC locus essential for autoimmune type I diabetes in the Komeda Diabetes-Prone ratAn orthologous non-MHC locus in rats and mice is linked to CD4(+) and CD8(+) T-cell proportion.Generation of a high-density rat EST map.Diabetes and hypertension in rodent models.Mapping baroreceptor function to genome: a mathematical modeling approach.
P2860
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P2860
Genetic dissection of autoimmune type I diabetes in the BB rat.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Genetic dissection of autoimmune type I diabetes in the BB rat.
@en
Genetic dissection of autoimmune type I diabetes in the BB rat.
@nl
type
label
Genetic dissection of autoimmune type I diabetes in the BB rat.
@en
Genetic dissection of autoimmune type I diabetes in the BB rat.
@nl
prefLabel
Genetic dissection of autoimmune type I diabetes in the BB rat.
@en
Genetic dissection of autoimmune type I diabetes in the BB rat.
@nl
P2093
P2860
P356
P1433
P1476
Genetic dissection of autoimmune type I diabetes in the BB rat.
@en
P2093
P2860
P2888
P356
10.1038/NG0992-56
P407
P50
P577
1992-09-01T00:00:00Z