about
Ion Channels in the HeartCaMKII-dependent regulation of cardiac Na(+) homeostasisNa+ channel function, regulation, structure, trafficking and sequestrationPost-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasFRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility.Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.CaMKII comes of age in cardiac health and disease.Interplay of voltage and Ca-dependent inactivation of L-type Ca current.Nonequilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricleHuman atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation.Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials.Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias.In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia.Ca/calmodulin kinase II differentially modulates potassium currents.Ranolazine for congenital and acquired late INa-linked arrhythmias: in silico pharmacological screening.Logistic regression analysis of populations of electrophysiological models to assess proarrythmic riskHow does β-adrenergic signalling affect the transitions from ventricular tachycardia to ventricular fibrillation?Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes.Predominant contribution of L-type Cav1.2 channel stimulation to impaired intracellular calcium and cerebral artery vasoconstriction in diabetic hyperglycemia.Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization.Quantitative analysis of the Ca2+ -dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes.β-adrenergic effects on cardiac myofilaments and contraction in an integrated rabbit ventricular myocyte model.Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII.Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytesRevealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity.Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics.Potassium channels in the heart: structure, function and regulation.In Silico Assessment of Efficacy and Safety of IKur Inhibitors in Chronic Atrial Fibrillation: Role of Kinetics and State-Dependence of Drug Binding.Size matters, proportion too: coupling of experiments and theory reveals relative roles of K+ channels in action potential stability.Induction of NO synthase 2 in ventricular cardiomyocytes incubated with a conventional bicarbonate dialysis bath.Non-ion channel therapeutics for heart failure and atrial fibrillation: Are CaMKII inhibitors ready for clinical use?Erratum: "Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity" [Chaos 27, 093918 (2017)].Applications of Dynamic Clamp to Cardiac Arrhythmia Research: Role in Drug Target Discovery and Safety Pharmacology Testing.Calcium and potassium changes during haemodialysis alter ventricular repolarization duration: in vivo and in silico analysis.Cardiac response to hemodialysis with different cardiovascular tolerance: heart rate variability and QT interval analysis.Theoretical investigation of action potential duration dependence on extracellular Ca2+ in human cardiomyocytesPatients with complex arrhythmias during and after haemodialysis suffer from different regimens of potassium removalIn silico assessment of Y1795C and Y1795H SCN5A mutations: implication for inherited arrhythmogenic syndromesKeeping it short and (not so) simple: characterizing hERG kinetics with sinusoidal waves
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Q26829681-E92295B1-5526-475E-A04E-8449C260AC09Q26997372-70125066-C478-4425-A30B-791E10D25090Q27005721-8C608493-3D2F-4BF2-B780-410953A7D451Q28292930-482A47F5-2E3D-46F1-BCAE-EDA9DDBAE99FQ33622017-7C40124B-545A-4FBD-A105-DD8D798C557CQ33641630-08268C82-B7CB-40EB-A0B7-7786A4048AA0Q33839892-C52C637A-7C16-431B-8F09-D7E415CDCE7DQ34009049-A0186682-A483-456E-B448-5868A66BEDEBQ34994127-92811C09-8DAE-4A99-9EEC-3E37BD67A3ADQ35528532-1CB21C55-8D12-4101-A75A-9545D019B54BQ36156526-D22019C9-30BC-42AB-860A-C4CB84C52AAEQ36378229-2B7533CA-AD5A-4BD3-ADC5-4FB5D65622FAQ36667578-1B60ECA0-6A71-4517-AC33-FCE7BA7530A6Q37324217-BC4916A0-ECFE-4C53-9009-410311CDE7BCQ37495337-411825DC-77F4-488E-9793-E4CC6DC9DB3BQ37578522-1457150D-8227-417D-8786-732091CC8CAFQ37603469-4A8C9CC8-81B4-4835-8DE2-FACBC9990A31Q37631275-DC2FF211-C79C-49C2-8737-96CA84729049Q38717677-AEF1DB64-3C84-4E35-82D2-E4CC6CA25798Q38822819-C32A0BF7-8AED-442C-BAC6-B55428074BF9Q39069522-D247E3EF-DE41-4040-B484-1DF9AED5B372Q41337981-78F01B4E-040F-4749-8681-7F67D04AF794Q42218987-4CA529BF-37C2-4D61-98B8-F40E2BAEEBF5Q42452421-D9AEA76A-D7B4-4FC4-BAFA-C3434A01F0B3Q42540023-61C8ECB6-898E-4BA2-9520-2426E73E1D3DQ42694191-AD4E4D52-419B-4B72-9394-1D438DC44F3FQ43920140-D30B0265-8817-43B6-B9B0-89D2B2EF2265Q44505007-1A343D5B-8854-411B-997F-D26E402D0B3DQ46015261-757359CA-20D7-4E76-BFE4-BB603ACADE19Q46133227-6997CBCF-25DE-4136-A180-29E39C834892Q46748480-A34070E3-6AB7-431F-BC72-8BD729273C3DQ46792007-89A263D5-9F24-4431-A5E2-D980DE40B19BQ46837135-64472179-4A5F-4537-B1D2-C0C64209C8E1Q47721428-F5759518-4B0E-4941-B6A2-202DD56A3DFCQ50854390-30BE9831-A316-49A0-B2D1-48B35AAA76ECQ51171672-9BEBF3C5-9955-455B-A30B-841530507FFFQ56991271-30CCF887-95DD-47CF-AA43-8C496565F004Q56993312-427D837B-2FE2-4A8F-9CFE-A081CD36F736Q56996067-190A2BFB-3D7D-4305-A7C2-41F2302538B8Q88009830-281DFE3A-E9B6-4326-A15E-4220ECCD81A1
P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Eleonora Grandi
@ast
Eleonora Grandi
@en
Eleonora Grandi
@es
Eleonora Grandi
@nl
Eleonora Grandi
@sl
type
label
Eleonora Grandi
@ast
Eleonora Grandi
@en
Eleonora Grandi
@es
Eleonora Grandi
@nl
Eleonora Grandi
@sl
prefLabel
Eleonora Grandi
@ast
Eleonora Grandi
@en
Eleonora Grandi
@es
Eleonora Grandi
@nl
Eleonora Grandi
@sl
P106
P1153
24168413600
P21
P31
P496
0000-0002-4401-8857