The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment.
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HIF hydroxylase pathways in cardiovascular physiology and medicineMolecular mechanisms of ischemic preconditioning in the kidneyBridging Translation by Improving Preclinical Study Design in AKIIntermittent exposure to xenon protects against gentamicin-induced nephrotoxicity.Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injuryEffects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins.Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectivesP2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells.Hypoxia-inducible factor-1α causes renal cyst expansion through calcium-activated chloride secretion.Prolyl 4-hydroxylases, master regulators of the hypoxia response.Hypoxia as a key player in the AKI-to-CKD transition.The role of hypoxia and Morg1 in renal injury.HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond.miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischaemic preconditioning.HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.Treatment with a novel hypoxia-inducible factor hydroxylase inhibitor (TRC160334) ameliorates ischemic acute kidney injury.Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models.Cooperative Oxygen Sensing by the Kidney and Carotid Body in Blood Pressure Control.Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult.MORG1+/- mice are protected from histological renal damage and inflammation in a murine model of endotoxemia.Renal hypoxia in kidney disease: Cause or consequence?Structural Insight into the Prolyl Hydroxylase PHD2: A Molecular Dynamics and DFT Study
P2860
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P2860
The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
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2011年學術文章
@zh-hant
name
The protective effect of proly ...... is superior to EPO treatment.
@en
The protective effect of proly ...... is superior to EPO treatment.
@nl
type
label
The protective effect of proly ...... is superior to EPO treatment.
@en
The protective effect of proly ...... is superior to EPO treatment.
@nl
prefLabel
The protective effect of proly ...... is superior to EPO treatment.
@en
The protective effect of proly ...... is superior to EPO treatment.
@nl
P2093
P2860
P356
P1476
The protective effect of proly ...... is superior to EPO treatment.
@en
P2093
Carsten Willam
Gazi Türkoglu
Gunnar Schley
Kai-Uwe Eckardt
Kerstin U Amann
Wanja M Bernhardt
Zhendi Wang
P2860
P304
P356
10.1093/NDT/GFR379
P407
P577
2011-07-08T00:00:00Z