mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.
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Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsRegulation of global and specific mRNA translation by the mTOR signaling pathwayCancer cells exploit adaptive mitochondrial dynamics to increase tumor cell invasionIs REDD1 a Metabolic Éminence Grise?Left-right asymmetry in the light of TOR: An update on what we know so farMetformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent BiosynthesisTargeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour developmentLoss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and NeurodegenerationLoss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome cHuman biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.Autophagy is a signature of a signaling network that maintains hematopoietic stem cellsZanthoxylum alkylamides ameliorate protein metabolism disorder in STZ-induced diabetic rats.Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling.PRL2 links magnesium flux and sex-dependent circadian metabolic rhythmsA Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver.A time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiologyMito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice.Targeting the eIF4F translation initiation complex: a critical nexus for cancer developmentEnhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.Pluripotent stem cell energy metabolism: an updateTumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effectTGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression.The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe.The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer DevelopmentVirus-induced translational arrest through 4EBP1/2-dependent decay of 5'-TOP mRNAs restricts viral infection.Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated GenesMitochondrial quality control: Easy come, easy go3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants.Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndromeHigh-resolution genomic profiling of thyroid lesions uncovers preferential copy number gains affecting mitochondrial biogenesis loci in the oncocytic variants.The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation.nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAsmTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity.An evolutionary perspective of AMPK-TOR signaling in the three domains of life.GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesisAdaptive Benefits of Storage Strategy and Dual AMPK/TOR Signaling in Metabolic Stress Response.Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance.Loss of long-chain acyl-CoA synthetase isoform 1 impairs cardiac autophagy and mitochondrial structure through mechanistic target of rapamycin complex 1 activation.
P2860
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P2860
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
mTORC1 controls mitochondrial ...... dent translational regulation.
@en
mTORC1 controls mitochondrial ...... dent translational regulation.
@nl
type
label
mTORC1 controls mitochondrial ...... dent translational regulation.
@en
mTORC1 controls mitochondrial ...... dent translational regulation.
@nl
prefLabel
mTORC1 controls mitochondrial ...... dent translational regulation.
@en
mTORC1 controls mitochondrial ...... dent translational regulation.
@nl
P2093
P50
P1433
P1476
mTORC1 controls mitochondrial ...... dent translational regulation.
@en
P2093
Arnim Pause
Chadi Zakaria
Daina Avizonis
Julie St-Pierre
Kristina Sikström
Liang Zheng
Masahiro Morita
Meztli Arguello
Michael Pollak
Shannon McLaughlan
P304
P356
10.1016/J.CMET.2013.10.001
P577
2013-11-01T00:00:00Z