Overexpression of the growth arrest and DNA damage-induced 45alpha gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells. - Wikidata - wikimedia - TriplyDB

Overexpression of the growth arrest and DNA damage-induced 45alpha gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells.

Overexpression of the growth arrest and DNA damage-induced 45alpha gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells.

http://www.wikidata.org/entity/Q54443042

about

The Autoimmune Ecology Epigenetic Modulation as a Therapeutic Prospect for Treatment of Autoimmune Rheumatic Diseases Plasticity of DNA methylation in mouse T cell activation and differentiation Associations between the expression of epigenetically regulated genes and the expression of DNMTs and MBDs in systemic lupus erythematosus CD3Z hypermethylation is associated with severe clinical manifestations in systemic lupus erythematosus and reduces CD3ζ-chain expression in T cells.DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus.Metabolic control of the epigenome in systemic Lupus erythematosus.Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus.Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.Potential of epigenetic therapies in non-cancerous conditions.Abnormalities of T cell signaling in systemic lupus erythematosus.Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases cAMP-responsive element modulator (CREM)α protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus The real culprit in systemic lupus erythematosus: abnormal epigenetic regulation.T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity.The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus.Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate.Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus.PRKCZ methylation is associated with sunlight exposure in a North American but not a Mediterranean population.RNA-seq Analysis Reveals Unique Transcriptome Signatures in Systemic Lupus Erythematosus Patients with Distinct Autoantibody Specificities Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?A correlation study on the effects of DNMT1 on methylation levels in CD4(+) T cells of SLE patients.A possible role of HMGB1 in DNA demethylation in CD4+ T cells from patients with systemic lupus erythematosus Epigenetic mechanisms in lupus.Epigenetics in lupus.Epigenetic alterations in autoimmune rheumatic diseases.The therapeutic potential of epigenetics in autoimmune diseases.Gene expression and regulation in systemic lupus erythematosus.Epigenetic dysregulation in systemic lupus erythematosus.Critical role of DNA methylation in the pathogenesis of systemic lupus erythematosus: new advances and future challenges.Epigenetics in SLE.Epigenetic alterations underlying autoimmune diseases.DNA methylation alterations in the pathogenesis of lupus.Epigenetic Alterations in Cellular Immunity: New Insights into Autoimmune Diseases.Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3.Epigenetic involvement in etiopathogenesis and implications in treatment of systemic lupus erythematous.Translating epigenetics into clinic: focus on lupus.GADD45A plays a protective role against temozolomide treatment in glioblastoma cells.TLR2-ICAM1-Gadd45α axis mediates the epigenetic effect of selenium on DNA methylation and gene expression in Keshan disease.

P2860

Q26747427-676E288F-EE9C-4415-BEFF-83F237D4F20B Q28079715-D713D972-5BF8-44BF-84C9-5ADA5C2E2BEA Q28727793-3B6A5688-AD2B-4A21-9E57-539C987B50DC Q31101708-93AC8E3C-E63D-422B-BD91-B832ED20D206 Q33437524-AFE484A6-5251-4D7C-99AB-9806997892E8 Q33664826-539A2E01-1924-4629-84C7-F67315B21DD0 Q33664849-CAF90DDF-CD64-432B-90B4-C558DFA15254 Q33889455-1174128A-0371-48B8-8FA6-AFC1396CE736 Q34416018-14AE6733-3AE0-4E55-9DFD-DBF6C74AC0DE Q34742578-FF3040D0-0FCD-4030-98C5-B63C80596DDE Q35092855-A48B1C65-DEA9-44EF-81EC-25F6A20DAC12 Q35138390-5BFC7C5C-1E3D-499A-B957-5A609B181E3A Q35577576-633FCED5-55A9-4C34-BF64-5B494E222F7C Q35604631-B284790F-0E0F-4307-ABBF-A05A2841AE48 Q35723616-035ECE99-C72D-4B70-AB49-5A1C612C7398 Q35836112-6FD8FC00-4793-40DA-816C-66569240CF0A Q35840786-8E756730-39E0-45B5-AC76-0DAA8F01B3DA Q36015069-6DD42B61-6AAB-42AC-B6C3-2507675CFFAC Q36095555-AA26865C-E530-4182-8345-ED6D81EB14EF Q36104364-703BC47B-661A-4765-963A-721A42D37AD6 Q36190001-FC13D3CF-0566-48AB-BCE8-CB64D4C96DCE Q36257320-7938604A-053E-4B26-A466-8B921F96055F Q36412436-5F9D0527-9C68-482A-946A-3E6F31A538F0 Q37180644-16B2FDC3-9E9F-4CAF-BF3E-828695D27580 Q37284401-A1522645-37B9-41A0-BC49-99F6C058F67E Q37830732-D5E00086-A526-4213-B054-DC8664C8FEA4 Q37846094-F9304AEA-3624-4BDA-A05A-A84F9CB2F2D3 Q37967566-9B02B7CD-8CEC-4FB1-9088-6083A82D4FBF Q38125510-9BC46AEF-1FDF-4069-BB99-28734C4CA642 Q38152825-0DA1F55F-0B92-4A89-9873-28C30A137909 Q38197135-E47ADAEC-5E0C-4811-8364-7CB928CEA327 Q38650522-8A52602D-9A87-43D0-9850-3A880A25E5BB Q38694852-7563AD7A-E29C-4368-B7B6-D48A3030B7B9 Q38968975-E9F4A7BB-42BE-4ECD-88B3-5A02CDE5D16D Q39142245-D0762DE4-4DE9-4281-B59E-437ED4AB36BE Q39198445-64A35039-D3C1-4DCF-8CB4-68A1D4AE7574 Q39456337-217CE944-12A0-4F9E-80E6-5543BFB1A180 Q41228881-3A3D75B1-05D5-485B-B910-31244283213F Q41460271-98D54AB7-0F2C-4C56-BA79-28067FFFD7AC Q51516133-C7BF51A0-9749-44CD-8C08-84E12E9246C7

P2860

Overexpression of the growth arrest and DNA damage-induced 45alpha gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells.

http://www.wikidata.org/entity/Q54443042

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年学术文章

@wuu

2010年学术文章

@zh

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

2010年學術文章

@zh-hant

name

Overexpression of the growth a ...... emethylation in lupus T cells.

@en

Overexpression of the growth a ...... emethylation in lupus T cells.

@nl

type

label

Overexpression of the growth a ...... emethylation in lupus T cells.

@en

Overexpression of the growth a ...... emethylation in lupus T cells.

@nl

prefLabel

Overexpression of the growth a ...... emethylation in lupus T cells.

@en

Overexpression of the growth a ...... emethylation in lupus T cells.

@nl

P1433

Q54443042-A62C82C1-31D8-4C1D-B08E-95911D0D66CB

P1476

Q54443042-15671864-A06D-428E-B0D5-48C12C47C5A1

P2093

Q54443042-0CF4AE86-8A19-4E96-880A-47E0217FC7C1

Q54443042-154D0467-845B-4D99-B8FE-039D5BF014E9

Q54443042-26E4C97D-1EE5-4F34-9AF7-3CAD3745ADEF

Q54443042-304C07DA-9DAB-4AB2-8737-BDCD3A114D7D

Q54443042-3E13DAE2-8B42-416D-BBA4-FBFB0A78233D

Q54443042-3F85F794-083F-406F-8938-E0690695DAE6

Q54443042-42D8ABF5-32D3-40DD-934D-0F727964D619

Q54443042-5150DAFF-7989-4C26-82BC-123A99983618

Q54443042-75190F33-C756-41D4-9962-2D80EE070A6C

Q54443042-776D0530-E4C0-4591-AAE7-D4A0263B0B17

P2860

Q54443042-1A85A59E-5C33-4E85-9B9E-99A467CCF369

Q54443042-23BD21AF-E497-4E04-BFEC-6131287A84BC

Q54443042-323DD447-74D8-43F2-9B26-B3471755AA00

Q54443042-44CDC4D6-CD30-4DC9-AF81-6B6D69357623

Q54443042-55E50B3C-FE14-4C6E-8A0C-CED21076B2E5

Q54443042-56F7086A-14C2-47AF-9147-5455DCE68994

Q54443042-6F0E85E4-DE61-412C-AE01-B7D22068493C

Q54443042-734DE331-5A51-4959-9CD7-9FA10E6ADCAE

Q54443042-8180F14E-2824-4BA5-8966-474D13380B27

Q54443042-82FEE2EE-0417-4EEE-87A8-B3D3FBE60503

P304

Q54443042-9E52E6B0-3B4B-4AB8-9F35-1C99372B4B8F

P31

Q54443042-BB90121C-31E9-4418-83D5-0ABD5F8C9C8C

P356

Q54443042-3B83F06A-8195-4D81-B2F3-975F257D4F15

P433

Q54443042-50F3BF95-6D44-4F50-9539-394148E20C86

P478

Q54443042-9B3CEC37-25FA-4F1A-9381-3A940DC5C8BA

P577

Q54443042-2CE346A9-BDF4-462C-9016-24931005D063

P698

Q54443042-277142A3-5190-4924-A5CE-28F46D8D1DD4

P921

Q54443042-8792C2FF-45C6-4790-A247-5066DC997C30

P356

P1433

Arthritis and Rheumatism

P1476

Overexpression of the growth a ...... emethylation in lupus T cells.

@en

P2093

Bruce Richardson

http://www.w3.org/2001/XMLSchema#string

Fei Gao

http://www.w3.org/2001/XMLSchema#string

Hai Long

http://www.w3.org/2001/XMLSchema#string

Heng Yin

http://www.w3.org/2001/XMLSchema#string

Ming Zhao

http://www.w3.org/2001/XMLSchema#string

Nan Hu

http://www.w3.org/2001/XMLSchema#string

Qianjin Lu

http://www.w3.org/2001/XMLSchema#string

Sha Zhao

http://www.w3.org/2001/XMLSchema#string

Xiaoyan Wu

http://www.w3.org/2001/XMLSchema#string

Xiujuan Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

The 1982 revised criteria for the classification of systemic lupus erythematosus

GADD45A does not promote DNA demethylation.

TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.

Epigenetics in human autoimmunity. Epigenetics in autoimmunity - DNA methylation in systemic lupus erythematosus and beyond.

Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.

p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes.

Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice.

DNA methylation and autoimmune disease.

Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus?

DNA methylation and systemic lupus erythematosus.

P304

1438-1447

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/ART.27363

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

62

http://www.w3.org/2001/XMLSchema#string

P577

2010-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20131288

http://www.w3.org/2001/XMLSchema#string

P921