Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. - Wikidata - wikimedia - TriplyDB

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

http://www.wikidata.org/entity/Q54443542

about

Subtype specific elevated expression of hyaluronidase-1 (HYAL-1) in epithelial ovarian cancer Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors Emerging and Evolving Ovarian Cancer Animal Models Models of endometriosis and their utility in studying progression to ovarian clear cell carcinoma Endometriosis and ovarian cancer: links, risks, and challenges faced Current status and evolution of preclinical drug development models of epithelial ovarian cancer Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN Antigen-specific immunotherapy of cervical and ovarian cancer Retrospective analysis of survival improvement by molecular biomarker-based personalized chemotherapy for recurrent ovarian cancer.Identification of novel therapeutic targets in microdissected clear cell ovarian cancers Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer.Dysregulated estrogen receptor signaling in the hypothalamic-pituitary-ovarian axis leads to ovarian epithelial tumorigenesis in mice Advances in tumor screening, imaging, and avatar technologies for high-grade serous ovarian cancer.Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.Endometrioid epithelial ovarian cancer : 20 years of prospectively collected data from a single center.Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation.Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.IRS1 regulation by Wnt/beta-catenin signaling and varied contribution of IRS1 to the neoplastic phenotype.A genomic and transcriptomic approach for a differential diagnosis between primary and secondary ovarian carcinomas in patients with a previous history of breast cancer The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions Minireview: physiological and pathological actions of RAS in the ovary.Frequent downregulation of miR-34 family in human ovarian cancers.Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context.Mouse models for cancer stem cell research.Tissue transglutaminase regulates β-catenin signaling through a c-Src-dependent mechanism.Roles of deletion of Arid1a, a tumor suppressor, in mouse ovarian tumorigenesis Ovarian cancer: pathology, biology, and disease models Comparative proteomic analysis of low stage and high stage endometrioid ovarian adenocarcinomas.Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice.Xenograft and Transgenic Mouse Models of Epithelial Ovarian Cancer and Non Invasive Imaging Modalities to Monitor Ovarian Tumor Growth In situ -Applications in Evaluating Novel Therapeutic Agents.Induction of papillary carcinoma in human ovarian surface epithelial cells using combined genetic elements and peritoneal microenvironment.A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.Differential analysis of ovarian and endometrial cancers identifies a methylator phenotype Development of a syngeneic mouse model of epithelial ovarian cancer.Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics.Coming into focus: the nonovarian origins of ovarian cancer.Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.

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P2860

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

http://www.wikidata.org/entity/Q54443542

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年學術文章

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Mouse model of human ovarian e ...... PI3K/Pten signaling pathways.

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Mouse model of human ovarian e ...... PI3K/Pten signaling pathways.

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type

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Mouse model of human ovarian e ...... PI3K/Pten signaling pathways.

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Mouse model of human ovarian e ...... PI3K/Pten signaling pathways.

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David E Misek

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Donald R Schwartz

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