Functional classification of drugs by properties of their pairwise interactions.
about
When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transitionTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesWhat is synergy? The Saariselkä agreement revisitedIn vivo bioluminescent imaging (BLI): noninvasive visualization and interrogation of biological processes in living animalsStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewViral quasispecies evolutionOrigin and proliferation of multiple-drug resistance in bacterial pathogensThe emerging paradigm of network medicine in the study of human diseaseSynergy Maps: exploring compound combinations using network-based visualizationDual- and triple-acting agents for treating core and co-morbid symptoms of major depression: novel concepts, new drugsIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesOptimal drug synergy in antimicrobial treatmentsA differential drug screen for compounds that select against antibiotic resistanceEpistatic interaction maps relative to multiple metabolic phenotypesThe pharmaco -, population and evolutionary dynamics of multi-drug therapy: experiments with S. aureus and E. coli and computer simulationsTarget inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathwaysSearching for synergies: matrix algebraic approaches for efficient pair screeningA network inference method for large-scale unsupervised identification of novel drug-drug interactionsResource competition may lead to effective treatment of antibiotic resistant infectionsSynergistic and antagonistic drug combinations depend on network topologyDiscovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergiesQuantifying the Determinants of Evolutionary Dynamics Leading to Drug ResistancePopulation Density Modulates Drug Inhibition and Gives Rise to Potential Bistability of Treatment Outcomes for Bacterial InfectionsSequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic EfficacyChemogenomics and orthology-based design of antibiotic combination therapiesCase-specific potentiation of glioblastoma drugs by pterostilbeneSystematic identification of synergistic drug pairs targeting HIVPairwise network mechanisms in the host signaling response to coxsackievirus B3 infection.Chemogenetic fingerprinting by analysis of cellular growth dynamics.Combination chemical geneticsPositive epistasis drives the acquisition of multidrug resistance.Dynamic Proteomics: a database for dynamics and localizations of endogenous fluorescently-tagged proteins in living human cellsPrevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks.Nonoptimal microbial response to antibiotics underlies suppressive drug interactions.Antibiotic sensitivity profiles determined with an Escherichia coli gene knockout collection: generating an antibiotic bar code.Phenotypic landscape of a bacterial cellDrug interactions and the evolution of antibiotic resistance.Challenges of antibacterial discoveryMultidrug evolutionary strategies to reverse antibiotic resistance.Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.
P2860
Q21145725-F938B144-1D99-43F6-975E-63BFC2D1FB93Q24289511-762F3312-53E2-4228-8198-95F525296E29Q26782977-2F0BFCD9-C9AF-47F3-8A6D-244990BDB766Q27006069-9CD66C29-5B55-49B9-82DC-12465A530A70Q27008867-C4958E6B-7926-4D70-88D9-22AEF793F673Q27013917-46DE4D74-A260-46C3-B8C9-F07F2601A505Q27023284-81F61042-5613-4DAC-9AE6-7E79D0965995Q27026041-AE6404F5-DB53-4B20-B7D3-A23A2A6780FDQ27902355-343B41FF-81BE-46A5-AB7B-25B9B50F54B4Q28305100-19FB8CFC-3442-4FEC-BF95-42D643B8D0FFQ28388335-FFF35A6A-566D-4B10-A927-C3D2DF9DFF48Q28474170-618A73FE-8F02-411C-8663-FEC11818E54BQ28476461-A3FF6215-CD0F-4FF8-9B3D-91BAD602F248Q28477135-B18B69EF-E061-4B5A-8C80-0A69D80D0AC7Q28485988-F26E9F8A-A240-49DE-87B7-6A13ECA5EC21Q28533401-7C7822E7-DA23-4ED7-B30C-2062CA37EB6CQ28534896-0DAEE1E9-F0AE-4560-AE80-7472C3C3F382Q28536026-D332A1CD-0DB2-4C96-AC27-A40DAEDB895DQ28537662-7C39CD7D-68C5-4F7E-A2A0-2355B9F131C7Q28542101-2A454355-1F4E-4183-B991-D6B569969C44Q28546587-5A840057-BF8E-4FA6-B756-2C58F4691450Q28551034-14E51765-958D-4F0D-A8F2-4E1648C086D3Q28552830-CF0FAAB5-BF2F-4DCF-963A-6DC632DE15BDQ28554197-EADC57AB-2FD6-48BD-A015-91B967233008Q28817589-183F6AD5-745A-47D9-8550-9DA06DBBDF10Q29048651-FC0D0CC4-C78E-42F1-A001-A6E5F61CEEDCQ30422333-F72C529B-858A-45DC-B990-D201276EFA6FQ30434557-A03EEA62-6742-45A7-9024-A509E8A32DD0Q33362564-06567395-2A2F-4858-87B5-2CBC24F92985Q33378070-90EC1722-4DF0-456D-A92D-B48F17AF0839Q33486486-144133DC-AF2B-44E7-B3E3-6BC9C0AE4E6CQ33509783-2DFEBE2C-BA7E-42BD-985F-C1C4271839A5Q33723235-3C5FC1BD-4573-43D7-B97C-B7838318E404Q33726796-A2AE6789-3B65-4470-9566-E27FF3D44FFDQ33768891-335863BC-E166-40EF-BA12-3F2D7A9DCDDEQ33780274-893036D9-2CFE-4CCB-A6B4-262CEC0F4751Q33792926-48FD6CA1-2BB0-4A37-9C6B-A78CFA275123Q33793074-34031B48-3C7F-4F26-B459-561268CEBCD1Q33871101-EAC199E4-4781-4AC0-87D3-607E2F70A689Q33901935-AA010BBC-3CFB-4809-B540-49F46B6485CA
P2860
Functional classification of drugs by properties of their pairwise interactions.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Functional classification of drugs by properties of their pairwise interactions.
@en
Functional classification of drugs by properties of their pairwise interactions.
@nl
type
label
Functional classification of drugs by properties of their pairwise interactions.
@en
Functional classification of drugs by properties of their pairwise interactions.
@nl
prefLabel
Functional classification of drugs by properties of their pairwise interactions.
@en
Functional classification of drugs by properties of their pairwise interactions.
@nl
P2093
P2860
P356
P1433
P1476
Functional classification of drugs by properties of their pairwise interactions.
@en
P2093
Ariane I Tschumi
Pamela Yeh
Roy Kishony
P2860
P2888
P304
P356
10.1038/NG1755
P407
P577
2006-03-19T00:00:00Z