Polyploidy road to therapy-induced cellular senescence and escape. - Wikidata - wikimedia - TriplyDB

Polyploidy road to therapy-induced cellular senescence and escape.

Polyploidy road to therapy-induced cellular senescence and escape.

http://www.wikidata.org/entity/Q54486386

about

The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?The "virgin birth", polyploidy, and the origin of cancer Docetaxel-induced polyploidization may underlie chemoresistance and disease relapse Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal.Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence.Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence.Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide.Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice.Isogenic radiation resistant cell lines: development and validation strategies.Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer.Impact of Premature Senescence on Radiosensitivity Measured by High Throughput Cell-Based Assays.Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma.Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: implications for stem cell mitosis and centrosome dynamics.Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome.Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events.Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses.Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors.

P2860

Q26749064-D907100B-5F89-4A22-AAC4-38C29D4777F1 Q27024916-E2BD22E0-C21C-4E81-8F85-419E03AF0995 Q28087331-3C53D0BD-2E3F-413D-A4B1-21193BF58BA0 Q33590178-6625178A-63E3-4F4D-BF28-2A432F7C520F Q33728894-FFF4A7DA-1F37-4926-85E9-6C3AC66B858D Q33812688-0CA71A49-FB73-412E-AFA6-883AF5D91E9B Q36397010-A98817BC-6E32-4820-B5ED-BBB33E3A4A5E Q36772203-BD072376-AE27-4E67-A61F-33F534A7DBDD Q36780731-2C126BCB-3CA1-4BAE-A512-F1454E2A264C Q37705958-F9550D79-C2E8-4201-AFD1-FAC60D8AD564 Q38172298-BF86F93C-4262-4E8F-B478-7A8BBF6EBFC6 Q38218129-AD98B34A-DEE9-480C-B317-2CF825B10CAB Q38690266-F8037229-372A-4550-9F7C-BC4ACFF09609 Q38735639-32ECC51A-733F-48B8-A2EC-4BB48D6494F4 Q38989929-E52D190C-4D4E-4812-AB3F-4C2D5B7C5873 Q39269601-79969462-1622-4A70-86F0-C3A34F0BED31 Q40465017-399D2D16-3066-47EB-BABE-7BF337A21DF5 Q41599721-A9E564C1-4EB5-437C-AB9B-4FA8CFA4B6EE Q41984773-5B93E35E-D223-4047-B0B5-FF0D54E96BE0 Q46581912-6189FD3D-C9C7-429F-B841-E53C9C63709F

P2860

Polyploidy road to therapy-induced cellular senescence and escape.

http://www.wikidata.org/entity/Q54486386

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Polyploidy road to therapy-induced cellular senescence and escape.

@en

Polyploidy road to therapy-induced cellular senescence and escape.

@nl

type

label

Polyploidy road to therapy-induced cellular senescence and escape.

@en

Polyploidy road to therapy-induced cellular senescence and escape.

@nl

prefLabel

Polyploidy road to therapy-induced cellular senescence and escape.

@en

Polyploidy road to therapy-induced cellular senescence and escape.

@nl

P1433

Q54486386-38F29EEE-59EB-432B-84C6-B91BF409C896

P1476

Q54486386-8ED2F27A-37CD-4A4F-8466-D7B96628503C

P2093

Q54486386-0E25066C-1A57-46AB-9B08-8FF624AAF2ED

Q54486386-0E52AF02-E04A-41B6-8ABE-3E46B09B4085

Q54486386-278A8925-9B3A-44DC-8879-E9B2D5036D26

Q54486386-96737C9B-D7C6-4BDD-A42E-67A5B301C962

Q54486386-A48ABC0E-D901-4476-B3EB-63202586BE2F

Q54486386-D9D72C09-5948-40D4-B2AC-560F6089E0F1

Q54486386-DCEB72F4-65A6-4057-82B2-10F643B86D0A

Q54486386-F9FD5A69-6323-4B5D-A6E5-3A4B32296AFA

P2860

Q54486386-0418291C-31B4-47A7-8575-82243CAC3B3A

Q54486386-076EA7ED-6E89-4D18-B5DB-C8F76F068284

Q54486386-0F81E256-B633-4C90-818B-98DA14B27551

Q54486386-102600B4-7139-4E98-81A7-AB497594CFA0

Q54486386-14EEEB24-037A-4C61-967E-E8AEE4D165CB

Q54486386-23E8862B-30C9-4540-AC35-84F34123ED79

Q54486386-251F9DD3-81B6-4054-9890-2F2962527A49

Q54486386-26B47F91-1E2E-4FA4-AC3B-332A4CC9C167

Q54486386-2ECC308F-AE4F-4C21-8A24-51151AED9612

Q54486386-349845E6-C420-40E6-B67E-875F2A230CDE

P304

Q54486386-803BA01C-8855-4DEA-8688-675B3439BD55

P31

Q54486386-86AB1AAA-ECD4-4D11-8A14-393FC7DC7ED5

P356

Q54486386-9AB069C3-C326-4652-8CD5-05AF65420774

P433

Q54486386-605C3986-7A2A-48B2-B752-3157741ECB5E

P478

Q54486386-CFCCC7A9-AA1F-474C-925D-C1CA70039EC8

P577

Q54486386-91A08C9D-ABE4-4703-839E-797FE963DA36

P698

Q54486386-86B0A24D-1F07-406D-9939-63912332BAFB

P356

P1433

International Journal of Cancer

P1476

Polyploidy road to therapy-induced cellular senescence and escape.

@en

P2093

Daniel Y Wu

http://www.w3.org/2001/XMLSchema#string

David Z Dong

http://www.w3.org/2001/XMLSchema#string

Elizabeth Chu

http://www.w3.org/2001/XMLSchema#string

Hubert Vesselle

http://www.w3.org/2001/XMLSchema#string

Iana Ivanova

http://www.w3.org/2001/XMLSchema#string

Peter C Wu

http://www.w3.org/2001/XMLSchema#string

Qin Wang

http://www.w3.org/2001/XMLSchema#string

Steven Zeliadt

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

Endopolyploidy in irradiated p53-deficient tumour cell lines: persistence of cell division activity in giant cells expressing Aurora-B kinase

CDK inhibitors: positive and negative regulators of G1-phase progression

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase

Expression of coxsackie and adenovirus receptor distinguishes transitional cancer states in therapy-induced cellular senescence

Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair.

Role of senescence and mitotic catastrophe in cancer therapy.

P304

1505-1515

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/IJC.27810

http://www.w3.org/2001/XMLSchema#string

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

132

http://www.w3.org/2001/XMLSchema#string

P577

2012-11-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

22945332

http://www.w3.org/2001/XMLSchema#string