Polyploidy road to therapy-induced cellular senescence and escape.
about
The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?The "virgin birth", polyploidy, and the origin of cancerDocetaxel-induced polyploidization may underlie chemoresistance and disease relapseThree steps to the immortality of cancer cells: senescence, polyploidy and self-renewal.Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markersIscador Qu inhibits doxorubicin-induced senescence of MCF7 cellsPolyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence.Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence.Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide.Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice.Isogenic radiation resistant cell lines: development and validation strategies.Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer.Impact of Premature Senescence on Radiosensitivity Measured by High Throughput Cell-Based Assays.Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma.Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: implications for stem cell mitosis and centrosome dynamics.Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome.Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events.Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cellsCombined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses.Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors.
P2860
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P2860
Polyploidy road to therapy-induced cellular senescence and escape.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Polyploidy road to therapy-induced cellular senescence and escape.
@en
Polyploidy road to therapy-induced cellular senescence and escape.
@nl
type
label
Polyploidy road to therapy-induced cellular senescence and escape.
@en
Polyploidy road to therapy-induced cellular senescence and escape.
@nl
prefLabel
Polyploidy road to therapy-induced cellular senescence and escape.
@en
Polyploidy road to therapy-induced cellular senescence and escape.
@nl
P2093
P2860
P356
P1476
Polyploidy road to therapy-induced cellular senescence and escape.
@en
P2093
Daniel Y Wu
David Z Dong
Elizabeth Chu
Hubert Vesselle
Iana Ivanova
Peter C Wu
Steven Zeliadt
P2860
P304
P356
10.1002/IJC.27810
P577
2012-11-16T00:00:00Z