Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.
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Multivalent Carbohydrate-Lectin Interactions: How Synthetic Chemistry Enables Insights into Nanometric RecognitionFine-tuning of prototype chicken galectins: structure of CG-2 and structure-activity correlationsNatural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cellsGalectin fingerprinting in naso-sinusal diseases.Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2011-2012.Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surfaceNoninvasive imaging of sialyltransferase activity in living cells by chemoselective recognition.Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides.Synthetic Mucin-Like Glycopeptides as Versatile Tools to Measure Effects of Glycan Structure/Density/Position on the Interaction with Adhesion/Growth-Regulatory Galectins in Arrays.Direct Enzymatic Branch-End Extension of Glycocluster-Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity.Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healingOnco-Golgi: Is Fragmentation a Gate to Cancer Progression?Galectin-3 Induces a Pro-degradative/inflammatory Gene Signature in Human Chondrocytes, Teaming Up with Galectin-1 in Osteoarthritis Pathogenesis.Glycophenotyping of osteoarthritic cartilage and chondrocytes by RT-qPCR, mass spectrometry, histochemistry with plant/human lectins and lectin localization with a glycoproteinContext-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target.The third dimension of reading the sugar code by lectins: design of glycoclusters with cyclic scaffolds as tools with the aim to define correlations between spatial presentation and activity.Introduction to glycopathology: the concept, the tools and the perspectivesGalectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-κB-Regulated Gene Network.Conformational selection in glycomimetics: human galectin-1 only recognizes syn-Ψ-type conformations of β-1,3-linked lactose and its C-glycosyl derivative.Lectins: getting familiar with translators of the sugar code.Sialic acids: biomarkers in endocrinal cancers.Sialyltransferase ST3GAL6 mediates the effect of microRNA-26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathwaySweet complementarity: the functional pairing of glycans with lectins.Impaired ATP6V0A2 expression contributes to Golgi dispersion and glycosylation changes in senescent cells.Comparative lectinology: Delineating glycan-specificity profiles of the chicken galectins using neoglycoconjugates in a cell assay.Sialylation of N-glycans: mechanism, cellular compartmentalization and function.Lipid glycosylation: a primer for histochemists and cell biologists.Galectins: their network and roles in immunity/tumor growth control.Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context.Regulatory Impact of Amniotic Membrane Transplantation on Presence of Adhesion/Growth-Regulatory Galectins-1 and -7 in Corneal Explants from Acanthamoeba Keratitis Patients: Clinical Note.Structural significance of galectin design: impairment of homodimer stability by linker insertion and partial reversion by ligand presence.Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression.Galectin-1 is a diagnostic marker involved in thyroid cancer progression.Preliminary X-ray crystallographic analysis of an engineered variant of human chimera-type galectin-3 with a shortened N-terminal domain.Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins.Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca²⁺ influx.Synthetic polyamine BPA-C8 inhibits TGF-β1-mediated conversion of human dermal fibroblast to myofibroblasts and establishment of galectin-1-rich extracellular matrix in vitro.Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin.Defining the potential of aglycone modifications for affinity/selectivity enhancement against medically relevant lectins: synthesis, activity screening, and HSQC-based NMR analysis.Studying the Structural Significance of Galectin Design by Playing a Modular Puzzle: Homodimer Generation from Human Tandem-Repeat-Type (Heterodimeric) Galectin-8 by Domain Shuffling.
P2860
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P2860
Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Tumour suppressor p16
@nl
Tumour suppressor p16(INK4a) ...... a pancreatic carcinoma model.
@en
type
label
Tumour suppressor p16
@nl
Tumour suppressor p16(INK4a) ...... a pancreatic carcinoma model.
@en
prefLabel
Tumour suppressor p16
@nl
Tumour suppressor p16(INK4a) ...... a pancreatic carcinoma model.
@en
P2093
P2860
P50
P356
P1433
P1476
Tumour suppressor p16(INK4a) ...... a pancreatic carcinoma model.
@en
P2093
Hanna Eriksson
Joachim C Manning
Katharina M Detjen
Maho Amano
Shin-Ichiro Nishimura
P2860
P304
P356
10.1111/FEBS.12001
P407
P577
2012-11-01T00:00:00Z