Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. - Wikidata - wikimedia - TriplyDB

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

http://www.wikidata.org/entity/Q54558350

about

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin Wnt signaling: the good and the bad Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer Frizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat Cancer Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs Mouse models for the discovery of colorectal cancer driver genes Single and Multiple Gene Manipulations in Mouse Models of Human Cancer Mouse models of intestinal cancer Colorectal cancer models for novel drug discovery Animal models of colorectal cancer Colon cryptogenesis: asymmetric budding Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration.Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine Inflammation and proliferation act together to mediate intestinal cell fusion The role of testosterone in colorectal carcinoma: pathomechanisms and open questions Genetically engineered mouse models in oncology research and cancer medicine Mouse models of colorectal cancer as preclinical models Hedgehog signaling and the Gli code in stem cells, cancer, and metastases Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis A common role for various human truncated adenomatous polyposis coli isoforms in the control of beta-catenin activity and cell proliferation A critical role for Apc in hematopoietic stem and progenitor cell survival Assembly of the cochlear gap junction macromolecular complex requires connexin 26.Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2.Alpha-catenin is essential in intestinal adenoma formation Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene Essential role of beta-catenin in postnatal bone acquisition A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.A highly efficient recombineering-based method for generating conditional knockout mutations Comprehensive behavioral analysis of voltage-gated calcium channel beta-anchoring and -regulatory protein knockout mice The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.Mammary tumor induction and premature ovarian failure in ApcMin mice are not enhanced by Brca2 deficiency.A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine.A medaka model of cancer allowing direct observation of transplanted tumor cells in vivo at a cellular-level resolution.Insights into cancer from transgenic mouse models.Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.Developmental defects and tumor predisposition in Rb mutant mice.

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P2860

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

http://www.wikidata.org/entity/Q54558350

description

1997 nî lūn-bûn

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1997年の論文

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

@zh-my

1997年学术文章

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1997年學術文章

@yue

1997年學術文章

@zh-hant

name

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

@en

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

@nl

type

label

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

@en

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

@nl

prefLabel

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

@en

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

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Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

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Akiyama T

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Hasegawa S

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Hirota M

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Ito M

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Kanamaru R

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Kanegae Y

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Matsumoto H

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Nakamura Y

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Noda T

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Saito I

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P2860

Identification of deletion mutations and three new genes at the familial polyposis locus

A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome.

The APC gene product in normal and tumor cells.

Adenovirus-mediated in vivo gene transfer.

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