Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.
about
Evolutionary divergence and functions of the human interleukin (IL) gene familyThe ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokineThe human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membraneThe N-terminal cytokine binding domain of LIFR is required for CNTF binding and signalingFunction and molecular modeling of the interaction between human interleukin 6 and its HNK-1 oligosaccharide ligandsLigand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptorReceptor recognition by gp130 cytokines.Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases.Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130.Interleukin-6: structure-function relationships.The immunoglobulin-like module of gp130 is required for signaling by interleukin-6, but not by leukemia inhibitory factor.Roles of IL-6 in Ocular Inflammation: A Review.Involvement of corneal epithelial cells in the Th17 response in an in vitro bacterial inflammation model.Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.Replacing factor-dependency with that for lysozyme: affordable culture of IL-6-dependent hybridoma by transfecting artificial cell surface receptor.Carbohydrate recognition site of interleukin-2 in relation to cell proliferation.Growth control of hybridoma cells with an artificially induced EpoR-gp130 heterodimer.Mechanistic pharmacokinetic/target engagement/pharmacodynamic (PK/TE/PD) modeling in deciphering interplay between a monoclonal antibody and its soluble target in cynomolgus monkeys.Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signalingDynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane.The N-terminus of gp130 is critical for the formation of the high-affinity interleukin-6 receptor complex.Recombinant human single chain Fv antibodies recognizing human interleukin-6. Specific targeting of cytokine-secreting cells.Characterization of an Antagonist Interleukin-6 Dimer by Stable Isotope Labeling, Cross-linking, and Mass Spectrometry
P2860
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P2860
Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Influence of interleukin-6 (IL ...... xameric IL-6.receptor complex.
@en
Influence of interleukin-6
@nl
type
label
Influence of interleukin-6 (IL ...... xameric IL-6.receptor complex.
@en
Influence of interleukin-6
@nl
prefLabel
Influence of interleukin-6 (IL ...... xameric IL-6.receptor complex.
@en
Influence of interleukin-6
@nl
P2093
P2860
P50
P356
P1476
Influence of interleukin-6 (IL ...... exameric IL-6.receptor complex
@en
P2093
A Hammacher
G J Howlett
J Weinstock
R L Moritz
P2860
P304
20138-20144
P356
10.1074/JBC.271.33.20138
P407
P577
1996-08-01T00:00:00Z