CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130
about
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptorInduction of the intronic enhancer of the human ciliary neurotrophic factor receptor (CNTFRalpha) gene by the TR4 orphan receptor. A member of steroid receptor superfamilyCloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transductionCloning and characterization of a specific receptor for mouse oncostatin MCrystal structure of a cytokine-binding region of gp130.Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activationLeukemia inhibitory factor, a cytokine at the interface between neurobiology and immunologyActivation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cellsCiliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesityRemoval of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cellsc-Cbl-dependent monoubiquitination and lysosomal degradation of gp130Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cellsInflammation and Alzheimer's diseaseDifferential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathwaysCiliary neurotrophic factor induces acute-phase protein expression in hepatocytesThe conserved box 1 motif of cytokine receptors is required for association with JAK kinasesSignaling of type II oncostatin M receptorBox 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at RasDistinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transductionCloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin-6 signal transducer gp130Identification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative promoter usageFunctional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130n-Butylidenephthalide (BP) maintains stem cell pluripotency by activating Jak2/Stat3 pathway and increases the efficiency of iPS cells generationPhosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6Phosphorylation and internalization of gp130 occur after IL-6 activation of Jak2 kinase in hepatocytesCNTF receptor subunit α as a marker for glioma tumor-initiating cells and tumor grade: laboratory investigation.Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor CombinationThe transcriptome of utricle hair cell regeneration in the avian inner ear.Xenopus muscle-specific kinase: molecular cloning and prominent expression in neural tissues during early embryonic development.Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.CD133+ adult human retinal cells remain undifferentiated in Leukaemia Inhibitory Factor (LIF)Peripheral nerve regeneration and neurotrophic factors.Lack of interleukin-6 (IL-6) enhances susceptibility to infection but does not alter latency or reactivation of herpes simplex virus type 1 in IL-6 knockout miceTransient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic miceD1 cap region involved in the receptor recognition and neural cell survival activity of human ciliary neurotrophic factorSalivary histatin 5 and human neutrophil defensin 1 kill Candida albicans via shared pathways.The human granulocyte-macrophage colony-stimulating factor receptor is capable of initiating signal transduction in NIH3T3 cells.Inter-species chimeras of leukaemia inhibitory factor define a major human receptor-binding determinantSignaling pathway of ciliary neurotrophic factor in neuroblastoma cell lines.
P2860
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P2860
CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@ast
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@en
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@nl
type
label
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@ast
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@en
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@nl
prefLabel
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@ast
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@en
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@nl
P2093
P1433
P1476
CNTF and LIF act on neuronal c ...... ucing receptor component gp130
@en
P2093
D J Anderson
K Yasukawa
S J Birren
T G Boulton
T Kishimoto
P304
P356
10.1016/0092-8674(92)90634-O
P407
P577
1992-06-26T00:00:00Z