Probing gene expression in live cells, one protein molecule at a time.
about
DNA replication at the single-molecule levelNature, nurture, or chance: stochastic gene expression and its consequencesSingle-RNA counting reveals alternative modes of gene expression in yeastA whole-cell computational model predicts phenotype from genotypeNon-genetic heterogeneity from stochastic partitioning at cell divisionUsing variability in gene expression as a tool for studying gene regulationTranscription goes digitalImaging flow cytometry: coping with heterogeneity in biological systemsShedding light on protein folding, structural and functional dynamics by single molecule studiesProtein expression analyses at the single cell levelGeneration and filtering of gene expression noise by the bacterial cell cycle.Phase correlation imaging of unlabeled cell dynamicsMechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells.The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility burstsNoise contributions in an inducible genetic switch: a whole-cell simulation studyEpigenetic and conventional regulation is distributed among activators of FLO11 allowing tuning of population-level heterogeneity in its expressionThe cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1Microbial cell individuality and the underlying sources of heterogeneityQuantitative characteristics of gene regulation by small RNARegulatory control and the costs and benefits of biochemical noiseNonidentifiability of the source of intrinsic noise in gene expression from single-burst dataEffect of promoter architecture on the cell-to-cell variability in gene expressionNon-equilibrium hyperbolic transport in transcriptional regulationVibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductaseEffects of cell-cycle-dependent expression on random fluctuations in protein levelsDeciphering Transcriptional Dynamics In Vivo by Counting Nascent RNA MoleculesNoise in biologyIntraclonal protein expression heterogeneity in recombinant CHO cellsNeuronal network analyses: premises, promises and uncertaintiesBiology by design: reduction and synthesis of cellular components and behaviourQuantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single CellsFunctional roles for noise in genetic circuitsStochastic profiling of transcriptional regulatory heterogeneities in tissues, tumors and cultured cellsIntersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression.Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentusCharacterization and application of single fluorescent nanodiamonds as cellular biomarkers.Hierarchical effector protein transport by the Salmonella Typhimurium SPI-1 type III secretion system.Investigating intracellular dynamics of FtsZ cytoskeleton with photoactivation single-molecule trackingTemporal switching and cell-to-cell variability in Ca2+ release activity in mammalian cells.Frequency-modulated nuclear localization bursts coordinate gene regulation.
P2860
Q22121971-C8126AA1-AF58-4940-8F40-579B30260802Q24610764-07CC6B3D-143D-42C8-A61E-647A4F119573Q24619115-82644DB2-437F-4ABF-A3A3-D2601F084BFCQ24622101-28D522AD-0F62-4FE4-B21A-81DA779EEC94Q24631799-A7BE9E9F-78B6-43AF-8816-6D1E1E48C205Q26864131-975C471B-2CA5-4F99-B973-88C49C5B339FQ26864339-9C11AA2F-8AF7-4396-8974-E19D0BA67C0BQ26996347-301409E0-C5C2-4216-AD23-2EBFEEED69BAQ26999437-6E838873-F0BB-40AE-AF69-D74C76937AAEQ27027088-329B2892-7CDE-4410-A494-D0ABC96AAB72Q27305053-8ED4AFA2-5A24-4E77-95D5-109C5FF5436BQ27313245-F2009C1D-0935-4DC2-AA92-C0AEEECA814FQ27316297-A8A617F3-6ADA-4A9E-B09E-1361B55BD43FQ27317019-1743554C-4938-4893-ABBF-46AB950160D5Q27333733-21AC9C1B-8510-4774-9A13-054287B106E9Q27348976-AF45BA2D-FA80-4FCA-A279-8979BB8EF797Q27349314-302FDC39-89D2-47F5-B69A-CE4BFC30C478Q28252446-57A5E99C-7BD7-45EC-96CC-E53429E40DCAQ28469313-1896A84F-7E87-4BC1-AB2E-37979F947333Q28473536-D4DBE48B-05C6-4863-BEF9-4CED0D9CF655Q28473666-447FEF76-49C6-4ECE-B9A5-6534E0E3969CQ28477325-181F6894-1290-4CDD-BECE-DEF44A43A63CQ28478932-3A2AA7D3-3EA8-46AB-B20E-F7CE3CC668A1Q28485714-BAA6E385-3F5F-417A-BC95-5E9CC4B9AA6EQ28584416-7CD58107-7774-4037-A5A3-D1A57E39D102Q28607719-CCB40EBC-E24A-48B7-8F52-EA207B35D74EQ28659275-58861996-8A56-4476-AB0E-500A05D582D1Q28749557-60D6C159-CD82-4948-9B05-8F4CE10F77B4Q28750718-A337BB1D-39C8-453E-B093-F797339E87D2Q28754680-B4610B25-37FD-4B0E-A5A4-98D2ECC128EFQ29039105-45973A19-3528-454D-8632-B357B6F83F04Q29616625-892A9730-94A0-4AB9-9533-27CE1A0366EDQ30415094-71C1B644-9D33-4198-9C33-F0A54F4A4460Q30427503-59AE568F-A03E-4DDE-991E-12D2394B9FBDQ30477816-DBFA5D99-2F17-4923-84F6-0ADFB21BBB09Q30478887-95248A6E-7A55-4B60-ABC7-DD045804DB08Q30481825-D34AA88C-8083-4548-9B9B-6383D379373EQ30482840-9C9C7D59-F021-498D-821D-E153622057AFQ30487156-34525472-614E-4AC1-B27F-6AA03C193BAAQ30488197-9AE0180B-84A7-424F-9E3E-D7FF8037ADF7
P2860
Probing gene expression in live cells, one protein molecule at a time.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Probing gene expression in live cells, one protein molecule at a time.
@en
Probing gene expression in live cells, one protein molecule at a time.
@nl
type
label
Probing gene expression in live cells, one protein molecule at a time.
@en
Probing gene expression in live cells, one protein molecule at a time.
@nl
prefLabel
Probing gene expression in live cells, one protein molecule at a time.
@en
Probing gene expression in live cells, one protein molecule at a time.
@nl
P2093
P356
P1433
P1476
Probing gene expression in live cells, one protein molecule at a time.
@en
P2093
P304
P356
10.1126/SCIENCE.1119623
P407
P577
2006-03-01T00:00:00Z