Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.
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Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiationGerminal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)Responses to Microbial Challenges by SLAMF ReceptorsStructure of CD84 provides insight into SLAM family functionA polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activationHomotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentAnalysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2SLAM-family receptors: immune regulators with or without SAP-family adaptors.Identification of SLAMF3 (CD229) as an inhibitor of hepatocellular carcinoma cell proliferation and tumour progression.Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors.CRISPR-Mediated Slamf1Δ/Δ Slamf5Δ/Δ Slamf6Δ/Δ Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell DefectsThe receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development.Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances RORγt recruitment to the IL17A promoter in human T lymphocytesTargeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody ResponsesCutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells.Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo.The role of SLAM family receptors in immune cell signaling.Control points in NKT-cell development.SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation.Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens.Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosusX-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses.SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions.SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.The role of SAP and SLAM family molecules in the humoral immune response.Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination.Innate memory T cells.Novel anti-myeloma immunotherapies targeting the SLAM family of receptors.Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity.The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction.Slam haplotypes modulate the response to lipopolysaccharide in vivo through control of NKT cell number and functionAltered expression of signalling lymphocyte activation molecule (SLAM) family receptors CS1 (CD319) and 2B4 (CD244) in patients with systemic lupus erythematosus.Bioinformatics-based identification of miR-542-5p as a predictive biomarker in breast cancer therapy.Characterization of mouse CD229 (Ly9), a leukocyte cell surface molecule of the CD150 (SLAM) family.Signaling lymphocytic activation molecules Slam and cancers: friends or foes?Importance and mechanism of 'switch' function of SAP family adapters.
P2860
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P2860
Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Ly9 (CD229)-deficient mice exh ...... SLAM- and SAP-deficient mice.
@en
type
label
Ly9 (CD229)-deficient mice exh ...... SLAM- and SAP-deficient mice.
@en
prefLabel
Ly9 (CD229)-deficient mice exh ...... SLAM- and SAP-deficient mice.
@en
P2093
P1476
Ly9 (CD229)-deficient mice exh ...... SLAM- and SAP-deficient mice.
@en
P2093
Catherine J Huntoon
Daniel B Graham
David J McKean
Jan van Deursen
Megan M McCausland
Michael P Bell
Shane Crotty
William A Faubion
P304
P356
10.4049/JIMMUNOL.176.1.291
P407
P577
2006-01-01T00:00:00Z