Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatids.
about
Structural and mechanistic insights into type II trypanosomatid tryparedoxin-dependent peroxidasesTrypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stressBiosynthesis of trypanothione in Trypanosoma brucei brucei."Subversive" substrates for the enzyme trypanothione disulfide reductase: alternative approach to chemotherapy of Chagas disease.A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.Glutathionylspermidine metabolism in Escherichia coli. Purification, cloning, overproduction, and characterization of a bifunctional glutathionylspermidine synthetase/amidase.Trypanothione synthesis in crithidia revisited.Mobilization of mercury and arsenic in humans by sodium 2,3-dimercapto-1-propane sulfonate (DMPS)Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase.Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylasePurification and characterization of glutathione reductase (E.C. 1.8.1.7) from bovine filarial worms Setaria cerviPolyamines in microorganisms.Mechanisms of flavoprotein-catalyzed reactions.Novel biochemical pathways in parasitic protozoa.Biomedical science and the third world. Under the volcano. Trypanothione reductase.Molecular characterization of the trypanothione reductase gene from Crithidia fasciculata and Trypanosoma brucei: comparison with other flavoprotein disulphide oxidoreductases with respect to substrate specificity and catalytic mechanism.Site-directed mutagenesis of the redox-active cysteines of Trypanosoma cruzi trypanothione reductase.The Architecture of Thiol Antioxidant Systems among Invertebrate Parasites.Redox potential regulates binding of universal minicircle sequence binding protein at the kinetoplast DNA replication origin.Antitrypanosomal properties of Panax ginseng C. A. Meyer: new possibilities for a remarkable traditional drug.Enzymatic mechanism controls redox-mediated protein-DNA interactions at the replication origin of kinetoplast DNA minicircles.Recent advances in the biochemistry of polyamines in eukaryotes.Trypanothione reductase activity is prominent in metacyclic promastigotes and axenic amastigotes of Leishmania amazonesis. Evaluation of its potential as a therapeutic target.Antioxidant defense mechanisms in parasitic protozoa.Trypanosoma cruzi Coexpressing Ornithine Decarboxylase and Green Fluorescence Proteins as a Tool to Study the Role of Polyamines in Chagas Disease Pathology.Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculataKukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase.Antitrypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-L-methionine.Spermidine is essential for normal proliferation of trypanosomatid protozoa.Trypanosoma cruzi glutathione-binding proteins: immunogenicity during human and experimental Chagas' disease.Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata.
P2860
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P2860
Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatids.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh-hant
name
Identification of a novel, thi ...... e activity in trypanosomatids.
@en
Identification of a novel, thi ...... e activity in trypanosomatids.
@nl
type
label
Identification of a novel, thi ...... e activity in trypanosomatids.
@en
Identification of a novel, thi ...... e activity in trypanosomatids.
@nl
prefLabel
Identification of a novel, thi ...... e activity in trypanosomatids.
@en
Identification of a novel, thi ...... e activity in trypanosomatids.
@nl
P1476
Identification of a novel, thi ...... e activity in trypanosomatids.
@en
P2093
A H Fairlamb
P304
P356
10.1016/0166-6851(85)90037-4
P577
1985-02-01T00:00:00Z