CD59a is the primary regulator of membrane attack complex assembly in the mouse.
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Emerging Novel Therapies for Heart FailureComplement component c1q mediates mitochondria-driven oxidative stress in neonatal hypoxic-ischemic brain injury.Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice.Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in miceThe membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout miceLongitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59.The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injuryNeuromyelitis optica pathology in rats following intraperitoneal injection of NMO-IgG and intracerebral needle injury.Targeted mouse complement inhibitor CR2-Crry protects against the development of atherosclerosis in mice.Complement regulator CD59 protects against atherosclerosis by restricting the formation of complement membrane attack complex.Generation and phenotyping of mCd59a and mCd59b double-knockout miceCell surface complement regulators moderate experimental myasthenia gravis pathology.Epididymal C4b-binding protein is processed and degraded during transit through the duct and is not essential for fertilityThe protective role of CD59 and pathogenic role of complement in hepatic ischemia and reperfusion injurySix host-range restricted poxviruses from three genera induce distinct gene expression profiles in an in vivo mouse modelDeficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice.Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice.Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIgThe role of complement system in ocular diseases including uveitis and macular degeneration.CD59 underlines the antiatherosclerotic effects of C-phycocyanin on mice.Proteomic discovery of diverse immunity molecules in mammalian spermatozoa.Mouse Cd59b but not Cd59a is upregulated to protect cells from complement attack in response to inflammatory stimulation.Complement regulation and kidney diseases: recent knowledge of the double-edged roles of complement activation in nephrology.The role of complement inhibitors beyond controlling inflammation.Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma.The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility.Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice.Cutting edge: murine CD59a modulates antiviral CD4+ T cell activity in a complement-independent mannerBalancing role of nitric oxide in complement-mediated activation of platelets from mCd59a and mCd59b double-knockout mice.Complement factor H deficiency results in decreased neuroretinal expression of Cd59a in aged mice.CD59 or C3 are not requred for angiotensin II-dependent hypertension or hypertrophy in mice.CD59 blockade enhances antigen-specific CD4+ T cell responses in humans: a new target for cancer immunotherapy?Overexpression of Human CD55 and CD59 or Treatment with Human CD55 Protects against Renal Ischemia-Reperfusion Injury in Mice.Analysis of the promoters and 5'-UTR of mouse Cd59 genes, and of their functional activity in erythrocytes.The splenic marginal zone shapes the phenotype of leukemia B cells and facilitates their niche-specific retention and survival.
P2860
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P2860
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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name
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
@en
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
@nl
type
label
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
@en
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
@nl
prefLabel
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
@en
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
@nl
P2093
P1476
CD59a is the primary regulator of membrane attack complex assembly in the mouse
@en
P2093
Claire L Harris
Masashi Mizuno
Nader Omidvar
Rossen M Donev
Sivasankar Baalasubramanian
Wen-Chao Song
P304
P356
10.4049/JIMMUNOL.173.6.3684
P407
P50
P577
2004-09-01T00:00:00Z