about
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblastsInduction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit.
P4510
description
Zelllinie
@de
ceall-líne
@ga
cell line
@en
cellijn van een Homo sapiens
@nl
lignée cellulaire
@fr
name
IIICF/c
@de
IIICF/c
@en
IIICF/c
@fr
IIICF/c
@ga
IIICF/c
@nl
type
label
IIICF/c
@de
IIICF/c
@en
IIICF/c
@fr
IIICF/c
@ga
IIICF/c
@nl
altLabel
III-CF culture C
@en
III-CF/c
@en
prefLabel
IIICF/c
@de
IIICF/c
@en
IIICF/c
@fr
IIICF/c
@ga
IIICF/c
@nl