Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction. - Wikidata - wikimedia - TriplyDB

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

http://www.wikidata.org/entity/Q55025334

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Osteoblast Role in Rheumatic Diseases.TRAF6 regulates the effects of polarized maturation of tolerability: Marrow-derived dendritic cells on collagen-induced arthritis in mice.Role and mechanism of action of sclerostin in bone.Chronic systemic inflammation originating from epithelial tissues.Differential Effects of Inflammation on Bone and Response to Biologics in Rheumatoid Arthritis and Spondyloarthritis.Hormonal and systemic regulation of sclerostin.The role of stromal cells in inflammatory bone loss.Low-Density Lipoprotein Receptor-Related Proteins in Skeletal Development and Disease.Osteoporosis: The Result of an 'Aged' Bone Microenvironment.Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia.Sclerostin antibodies in osteoporosis: latest evidence and therapeutic potential.Osteoporosis treatment: bisphosphonates reign to continue for a few more years, at least?Targeting subchondral bone mesenchymal stem cell activities for intrinsic joint repair in osteoarthritis.Bone Loss in Rheumatoid Arthritis: Basic Mechanisms and Clinical Implications.Sclerostin: an Emerging Target for the Treatment of Cancer-Induced Bone Disease.SOST/Sclerostin Improves Post Traumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury.Effects of Teriparatide on Joint Erosions in Rheumatoid Arthritis: A Randomized Controlled Trial.Sclerostin expression and functions beyond the osteocyte.Application of anti-Sclerostin therapy in non-osteoporosis disease models.[Fibroblastic modulators of bone destruction].Amgen/UCB build on bone franchise with anti-sclerostin antibody.Early sclerostin expression explains bone formation inhibition before arthritis onset in the rat adjuvant-induced arthritis model.Bone erosions in rheumatoid arthritis: recent developments in pathogenesis and therapeutic implications Changes in bone density and bone turnover in patients with rheumatoid arthritis treated with rituximab, results from an exploratory, prospective study

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Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

http://www.wikidata.org/entity/Q55025334

description

2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

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name

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

@en

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

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type

label

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

@en

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

@nl

prefLabel

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

@en

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

@nl

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SCITRANSLMED.AAC4351

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Science Translational Medicine

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Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

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Adelheid Korb-Pap

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Annelena Held

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Athanasios Stratis

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Berno Dankbar

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Christoph Cromme

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Corinna Wehmeyer

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Denise Beckmann

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Ina Kramer

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Michaela Kneissel

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Michelle Fennen

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P2860

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

The Wnt signaling pathway in development and disease

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density

Mechanisms of Wnt signaling in development

Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.

Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease.

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330ra35

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330

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Christine Hartmann

Martin Böttcher

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2016-03-16T00:00:00Z

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27089204

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